PRO-IL-33 antibody


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WB IF ResetRabbit anti Human Pro-Interleukin-33
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- PRO-IL-33
Rabbit anti Human pro-interleukin-33 antibodyrecognises human pro-interleukin-33 (pro-IL-33). Pro-IL-33 is further processed into its mature secreted form, IL-33. IL-33, a cytokine formerly known as NF-HEV or nuclear factor from high endothelieal venules, belongs to the IL-1 super family which signals through interaction with the ST2 and Toll-interleukin 1 (IL-1) receptors, and is known to act as an immunoregulator of T helper 2 (Th2) cell cytokine synthesis. IL-33 is abundantly expressed in high endothelial venules found in tonsils, peyers patches and mesenteric lymph nodes. |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to human pro-interleukin-33 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide (NaN3)
- Immunogen
- A peptide sequence corresponding to an 19 amino acid sequence from near the amino terminus of Genbank accession No. NP_254274.
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Immunofluorescence | ![]() |
20ug/ml | |
Western Blotting | ![]() |
1.0 | 2.0ug/ml |
- Immunohistology
- This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.
- Histology Positive Control Tissue
- Human brain tissue
- Western Blotting
- AHP1626 detects a band of approximately 36kDa in human lymph node cell lysates.
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Description | TidyBlot Western Blot Detection Reagent:HRP |
- Synonyms
- NF-HEV
- RRID
- AB_2124143
- UniProt
- O95760
- Entrez Gene
- IL33
- GO Terms
- GO:0005125 cytokine activity
- GO:0005615 extracellular space
- GO:0043032 positive regulation of macrophage activation
- GO:0045944 positive regulation of transcription from RNA polymerase II promoter
- GO:0050729 positive regulation of inflammatory response
- GO:0090197 positive regulation of chemokine secretion
AHP1626

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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