Encoded by the PRMT1 gene, protein arginine N-methyltransferase 1 is a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of PRMT1 may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PRMT1, and a pseudogene of PRMT1 is located on the long arm of chromosome 5 (provided by RefSeq, Dec 2011).
Rabbit anti Human PRMT1 antibody detects a band of 42 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
- Target Species
- Western Blotting
- Anti PRMT1 detects a band of approximately 42 kDa in HEK293 cell lysates
- Product Form
- Purified IgG - liquid
- Rabbit Ig fraction prepared by ammonium sulphate precipitation
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- KLH conjugated synthetic peptide between 317-346 amino acids from the C-terminal region of human PRMT1
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- 12 months from date of despatch
- Entrez Gene
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- For research purposes only
Applications of PRMT1 antibody
|Application Name||Verified||Min Dilution||Max Dilution|
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
Secondary Antibodies Available
|Description||Product Code||Applications||Pack Size||List Price||Quantity|
|Goat anti Rabbit IgG (H/L):HRP||STAR208P||WB||2 ml|