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Prealbumin antibody

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Sheep anti Human Prealbumin

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
Prealbumin

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Technical Suppport
Product Code Applications Pack Size List Price Your Price Qty
AHP1837
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SDS Safety Datasheet SDS
ID 1 ml loader
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Sheep anti Human Prealbumin antibody recognises prealbumin, also known as transthyretin, a homotetrameric serum and cerebrospinal fluid protein which acts as a carrier for the thyroid hormone thyroxine. Each monomer is a 127 amino acid polypeptide. Prealbumin is synthesised principally in the liver and choroid plexus from where it is secreted into the serum and cerebrospinal fluid respectively.

Sheep anti Human Prealbumin antibody is also available as nephelometric grade whole serum and in bulk quantities. Please enquire for further details.

Target Species
Human
Product Form
Purified IgG - liquid
Preparation
IgG fractions prepared by ammonium sulphate precipitation and anion exchange chromatography
Antiserum Preparation
Antisera to human prealbumin were raised by repeated immunisation of sheep with highly purified antigen.
Buffer Solution
Glycine buffered saline
Preservative Stabilisers
0.09% Sodium Azide
0.1% EACA
0.01% Benzamidine
1mM EDTA
Immunogen
Human prealbumin.
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunodiffusion
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.

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References for Prealbumin antibody

  1. Lancaster, M.A. et al. (2013) Cerebral organoids model human brain development and microcephaly.
    Nature. 501 (7467): 373-9.
  2. Nguyen, D.N. et al. (2016) Oral antibiotics increase blood neutrophil maturation and reduce bacteremia and necrotizing enterocolitis in the immediate postnatal period of preterm pigs.
    Innate Immun. 22 (1): 51-62.
  3. Royer, P.J. et al. (2010) The mannose receptor mediates the uptake of diverse native allergens by dendritic cells and determines allergen-induced T cell polarization through modulation of IDO activity.
    J Immunol. 185 (3): 1522-31.
  4. Renner, M. et al. (2017) Self-organized developmental patterning and differentiation in cerebral organoids.
    EMBO J. 36 (10): 1316-29.
  5. Lancaster, M.A. et al. (2017) Guided self-organization and cortical plate formation in human brain organoids.
    Nat Biotechnol. 35 (7): 659-66.

Immunofluorescence

Synonyms
Transthyretin
RRID
AB_2212089
UniProt
P02766
Entrez Gene
TTR
GO Terms
GO:0005576 extracellular region
GO:0005179 hormone activity
GO:0005737 cytoplasm
GO:0006810 transport
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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