PPP2R1A antibody

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Anti PPP2R1A Antibody (PrecisionAb Polyclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with Goat anti HumanPPP2R1A antibody (**VPA00194**) followed by detection with HRP conjugated Donkey anti Sheep/Goat IgG (1/10,000, STAR88P) and visualized on the ChemiDoc MP with 7 second exposure. Arrow points to PPP2R1A (molecular weight 60 kDa).

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Goat anti PPP2R1A

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified
Specificity: PPP2R1A

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Product Code Applications Pack Size List Price Your Price Qty

List Price	Your Price
VPA00194 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
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Goat anti Human PPP2R1A antibody recognizes PPP2R1A, also known as PP2A subunit A isoform PR65-alpha, PP2A subunit A isoform R1-alpha, medium tumor antigen-associated 61 KDa protein, protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform, serine/threonine protein phosphatase 2A, 65 kDa regulatory subunit A, alpha isoform and serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform.

The PPP2R1A gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. PPP2R1A encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described (provided by RefSeq, Apr 2010).

Goat anti Human PPP2R1A antibody detects a band of 60 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Anti PPP2R1A detects a band of approximately 60 kDa in Jurkat cell lysates.
Species Cross-Reactivity: Target Species Cross Reactivity

Mouse

Rat; N.B. Antibody reactivity and working conditions may vary between species.
Product Form: Purified IgG - liquid
Preparation: Goat polyclonal antibody purified by affinity chromatography.
Buffer Solution: Tris buffered saline.
Preservative Stabilisers: 0.02% Sodium Azide (NaN₃)
0.5% Bovine Serum Albumin
Immunogen: Peptide with sequence C-KYFAQEALTVLSLA
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Target Species	Cross Reactivity
Mouse
Rat

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Donkey anti Sheep/Goat IgG:HRP	STAR88P	C E P WB	1 ml	Log in	Get Quote
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Description	Donkey anti Sheep/Goat IgG:HRP

UniProt: P30153
Entrez Gene: PPP2R1A
GO Terms: GO:0007059 chromosome segregation; GO:0000086 G2/M transition of mitotic cell cycle; GO:0000159 protein phosphatase type 2A complex; GO:0000188 inactivation of MAPK activity; GO:0000775 chromosome, centromeric region; GO:0016020 membrane; GO:0003823 antigen binding; GO:0005739 mitochondrion; GO:0005829 cytosol; View More GO Terms; GO:0005625 soluble fraction; GO:0005634 nucleus; GO:0006275 regulation of DNA replication; GO:0006461 protein complex assembly; GO:0006470 protein dephosphorylation; GO:0006672 ceramide metabolic process; GO:0006917 induction of apoptosis; GO:0008380 RNA splicing; GO:0008601 protein phosphatase type 2A regulator activity; GO:0010033 response to organic substance; GO:0015630 microtubule cytoskeleton; GO:0019932 second-messenger-mediated signaling; GO:0030111 regulation of Wnt receptor signaling pathway; GO:0030155 regulation of cell adhesion; GO:0030308 negative regulation of cell growth; GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein; GO:0045449 regulation of transcription; GO:0045595 regulation of cell differentiation; GO:0046982 protein heterodimerization activity