PPP1CC antibody

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Rabbit anti PPP1CC

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified

Product Code	Applications	Pack Size	Your Price	List Price	Quantity
VPA00357 Datasheet	WB SDS	100 µl	Log in		Get Quote

Rabbit anti Human PPP1CC antibody recognizes PPP1CC, also known as protein phosphatase 1C catalytic subunit, serine/threonine phosphatase 1 gamma and serine/threonine-protein phosphatase PP1-gamma catalytic subunit.

The protein encoded by the PPP1CC gene belongs to the protein phosphatase family, PP1 subfamily. PP1 is an ubiquitous serine/threonine phosphatase that regulates many cellular processes, including cell division. It is expressed in mammalian cells as three closely related isoforms, alpha, beta/delta and gamma, which have distinct localization patterns. PPP1CC encodes the gamma isozyme. Alternatively spliced transcript variants encoding different isoforms have been found for PPP1CC (provided by RefSeq, Oct 2011).

Rabbit anti Human PPP1CC antibody detects a band of 37 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species

Human

Western Blotting

Anti PPP1CC detects a band of approximately 37 kDa in HEK293 cell lysate

Species Cross-Reactivity

Target Species	Cross Reactivity
Mouse

N.B. Antibody reactivity and working conditions may vary between species.

Product Form

Ig fraction - liquid

Preparation

Rabbit Ig fraction prepared by ammonium sulphate precipitation

Buffer Solution

Phosphate buffered saline

Preservative Stabilisers

0.09% Sodium Azide (NaN₃)

Immunogen

KLH-conjugated synthetic peptide corresponding to aa 291-321 of human PPP1CC

Storage Information

Storage: Store undiluted at -20^oC, avoiding repeated freeze thaw cycles
Guarantee: 12 months from date of despatch

More Information

UniProt: P36873
Entrez Gene: PPP1CC
GO Terms: GO:0005515 protein binding; GO:0000236 mitotic prometaphase; GO:0000777 condensed chromosome kinetochore; GO:0005829 cytosol; GO:0004722 protein serine/threonine phosphatase activity; GO:0046872 metal ion binding; GO:0005730 nucleolus; GO:0005977 glycogen metabolic process; GO:0016607 nuclear speck; GO:0019433 triglyceride catabolic process; GO:0019901 protein kinase binding; GO:0030496 midbody; GO:0032154 cleavage furrow; GO:0051301 cell division; GO:0070688 MLL5-L complex; GO:0072357 PTW/PP1 phosphatase complex
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory: For research purposes only

Applications of PPP1CC antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description	Product Code	Applications	Pack Size	Your Price	List Price	Quantity
Goat anti Rabbit IgG (H/L):HRP	STAR208P	WB	2 ml	Log in		Get Quote

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