Poly [ADP-RIBOSE] Polymerase 3 antibody

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Rabbit anti Poly (ADP-Ribose) Polymerase 3

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Product Code Applications Pack Size List Price Quantity
VPA00523
Datasheet
WB
MSDS
100 µl loader

Rabbit anti Human poly [ADP-ribose] polymerase 3 antibody recognizes poly [ADP-ribose] polymerase 3 also known as PARP3, ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 3, ADP-ribosyltransferase diphtheria toxin-like 3, NAD(+) ADP-ribosyltransferase 3, IRT1 or poly[ADP-ribose] synthase 3.

The protein encoded by the PARP3 gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. PARP3 gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified (provided by RefSeq, Jul 2008).

Rabbit anti Human poly [ADP-ribose] polymerase 3 antibody detects a band of 71 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Anti poly [adp-ribose] polymerase 3 detects a band of approximately 71 kDa in HEK293 cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid.
Preparation
Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
Immunogen
KLH conjugated synthetic peptide corresponding to amino acid 99-126 of human poly [ADP-ribose] polymerase 3

Storage Information

Storage
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
Guarantee
12 months from date of despatch

More Information

UniProt
Q9Y6F1
Entrez Gene
PARP3
GO Terms
GO:0005515 protein binding
GO:0003950 NAD+ ADP-ribosyltransferase activity
GO:0005634 nucleus
GO:0005814 centriole
GO:0006281 DNA repair
GO:0006471 protein ADP-ribosylation
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories
Regulatory
For research purposes only.

Applications of Poly [ADP-RIBOSE] Polymerase 3 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rabbit IgG (H/L):HRP STAR208P WB 2 ml