Poly [ADP-RIBOSE] Polymerase 3 antibody
Rabbit anti Human poly [ADP-ribose] polymerase 3 antibody recognizes poly [ADP-ribose] polymerase 3 also known as PARP3, ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)-like 3, ADP-ribosyltransferase diphtheria toxin-like 3, NAD(+) ADP-ribosyltransferase 3, IRT1 or poly[ADP-ribose] synthase 3.
The protein encoded by the PARP3 gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. PARP3 gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified (provided by RefSeq, Jul 2008).
Rabbit anti Human poly [ADP-ribose] polymerase 3 antibody detects a band of 71 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
The protein encoded by the PARP3 gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. PARP3 gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified (provided by RefSeq, Jul 2008).
Rabbit anti Human poly [ADP-ribose] polymerase 3 antibody detects a band of 71 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti poly [adp-ribose] polymerase 3 detects a band of approximately 71 kDa in HEK293 cell lysates.
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid.
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline.
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3).
- Immunogen
- KLH conjugated synthetic peptide corresponding to amino acid 99-126 of human poly [ADP-ribose] polymerase 3
Storage Information
- Storage
- Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- Q9Y6F1
- Entrez Gene
- PARP3
- GO Terms
- GO:0005515 protein binding
- GO:0003950 NAD+ ADP-ribosyltransferase activity
- GO:0005634 nucleus
- GO:0005814 centriole
- GO:0006281 DNA repair
- GO:0006471 protein ADP-ribosylation
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
- Regulatory
- For research purposes only.
Applications of Poly [ADP-RIBOSE] Polymerase 3 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml |
