Pokemon antibody

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Rabbit anti Pokemon

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Product Code Applications Pack Size List Price Quantity
VPA00636
Datasheet
WB
SDS
100 µl loader

Rabbit anti Human pokemon antibody recognizes the zinc finger and BTB domain-containing protein 7A, also known as HIV-1 inducer of short transcripts binding protein, POZ and Krueppel erythroid myeloid ontogenic factor, TTF-I-interacting peptide 21 (TIP21), LRF or zinc finger protein 857A.

Based on its similarity to other proteins Zinc finger and BTB domain-containing, the protein encoded by ZBTB7A is believed to play a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals and/or to efficiently abrogate E2F1-dependent CDKN2A transactivation/de-repression. Expressed in medullary epithelial cells and Hassle's corpuscles in WT thymus and in the squamous epithelium as well as the germinal center lymphocytes in tonsils. The product of ZBTB7A is up-regulated in a subset of lymphomas, as well as in a subset of breast, lung, colon, prostate and bladder carcinomas (at protein level). ZBTB7A has been shown to interact with BCL6.

Rabbit anti Human pokemon antibody detects a band of 75 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Rabbit anti pokemon detects a band of approximately 75 kDa in HEK293 cell lysates
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
2% Sucrose
Immunogen
Synthetic peptide encompassing part of the N terminal region of human pokemon

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
Guarantee
12 months from date of despatch

More Information

UniProt
O95365
Entrez Gene
ZBTB7A
GO Terms
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0006350 transcription
GO:0007275 multicellular organismal development
GO:0008270 zinc ion binding
GO:0016564 transcription repressor activity
GO:0030154 cell differentiation
GO:0035035 histone acetyltransferase binding
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories
Regulatory
For research purposes only

Applications of Pokemon antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rabbit IgG (H/L):HRP STAR208P WB 2 ml