Plasminogen antibody

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Anti Plasminogen Antibody (PrecisionAb Polyclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates and human plasma probed with Goat anti Human plasminogen antibody (**VPA00152**) followed by detection with HRP conjugated Donkey anti Sheep/Goat IgG (1/10,000, STAR88P) and visualized on the ChemiDoc MP with 18 second exposure. Arrow points to plasminogen (molecular weight 100 kDa).

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Goat anti Plasminogen

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified
Specificity: Plasminogen

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VPA00152 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
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Goat anti Human plasminogen antibody recognizes plasminogen, a secreted blood zymogen.

Plasminogen is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in plasminogen are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for plasminogen (provided by RefSeq, Dec 2009).

Goat anti Human plasminogen antibody detects a band of 100 kDa. The antibody has been extensively validated for western blotting using human plasma lysates.

Target Species: Human
Western Blotting: Anti plasminogen detects a band of approximately 100 kDa in human plasma samples.
Product Form: Purified IgG - liquid
Preparation: Goat polyclonal antibody prepared by a multi-step process including salt fractionation and ion exchange chromatography.
Buffer Solution: Phosphate buffered saline.
Preservative Stabilisers: 0.09% Sodium Azide (NaN₃)
1% Bovine Serum Albumin
Immunogen: Plasminogen derived from human plasma
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

UniProt: P00747
Entrez Gene: PLG
GO Terms: GO:0002576 platelet degranulation; GO:0004252 serine-type endopeptidase activity; GO:0005615 extracellular space; GO:0008285 negative regulation of cell proliferation; GO:0010812 negative regulation of cell-substrate adhesion; GO:0022617 extracellular matrix disassembly; GO:0030168 platelet activation; GO:0031093 platelet alpha granule lumen; GO:0031232 extrinsic to external side of plasma membrane; View More GO Terms; GO:0034185 apolipoprotein binding; GO:0042730 fibrinolysis; GO:0043498 cell surface binding; GO:0048771 tissue remodeling; GO:0051918 negative regulation of fibrinolysis; GO:0051919 positive regulation of fibrinolysis