Plasminogen antibody

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Goat anti Plasminogen

Plasminogen antibody recognizes plasminogen, also known as plasmin. This antibody has been extensively validated for western blotting using whole cell lysates.

Product Type
PrecisionAb™ Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
VPA00152 WB 100 µl
Goat anti Human plasminogen antibody recognizes plasminogen, a secreted blood zymogen.

Plasminogen is activated by proteolysis and converted to plasmin and angiostatin. Plasmin dissolves fibrin in blood clots and is an important protease in many other cellular processes while angiostatin inhibits angiogenesis. Defects in plasminogen are likely a cause of thrombophilia and ligneous conjunctivitis. Two transcript variants encoding different isoforms have been found for plasminogen (provided by RefSeq, Dec 2009).

Goat anti Human plasminogen antibody detects a band of 100 kDa. The antibody has been extensively validated for western blotting using human plasma lysates.

Product Details

Target Species
Human
Western Blotting
Anti plasminogen detects a band of approximately 100 kDa in human plasma samples.
Product Form
Purified IgG - liquid
Preparation
Goat polyclonal antibody prepared by a multi-step process including salt fractionation and ion exchange chromatography
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
Immunogen
Plasminogen derived from human plasma
Instructions For Use
Please refer to the PrecisionAb western blotting protocol. For additional information on secondary antibody dilution and exposure time see product web page.

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
Shelf Life
As supplied, 12 months from date of despatch.

More Information

UniProt
P00747 Related reagents
Entrez Gene
PLG Related reagents
GO Terms
GO:0002576 platelet degranulation
GO:0004252 serine-type endopeptidase activity
GO:0005615 extracellular space
GO:0008285 negative regulation of cell proliferation
GO:0010812 negative regulation of cell-substrate adhesion
GO:0022617 extracellular matrix disassembly
GO:0030168 platelet activation
GO:0031093 platelet alpha granule lumen
GO:0031232 extrinsic to external side of plasma membrane
GO:0034185 apolipoprotein binding
GO:0042730 fibrinolysis
GO:0043498 cell surface binding
GO:0048771 tissue remodeling
GO:0051918 negative regulation of fibrinolysis
GO:0051919 positive regulation of fibrinolysis
Acknowledgements
PrecisionAbâ„¢ is a trademark of Bio-Rad Laboratories.
Regulatory
For research purposes only

Applications of Plasminogen antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

PrecisionAb antibodies have been extensively validated for the western blot application. The antibody has been validated at the suggested dilution. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependant on sample type.

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Donkey anti Sheep/Goat IgG:HRP STAR88P 1 ml C E P WB

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