PI-4 Kinase 2A antibody
Rabbit anti Human PI-4 kinase 2A antibody recognizes PI-4 kinase 2A, also known as phosphatidylinositol 4-kinase type II (PI4KII), phosphatidylinositol 4-kinase type 2A and phosphatidylinositol 4-kinase type II-alpha.
Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI-4 Kinase 2A phosphorylates PtdIns at the D-4 position, an essential step in the biosynthesis of PtdInsPs (Barylko et al. 2001 PubMed 11244087, OMIM, Mar 2008).
Rabbit anti Human PI-4 kinase 2A antibody detects a band of 54 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI-4 Kinase 2A phosphorylates PtdIns at the D-4 position, an essential step in the biosynthesis of PtdInsPs (Barylko et al. 2001 PubMed 11244087, OMIM, Mar 2008).
Rabbit anti Human PI-4 kinase 2A antibody detects a band of 54 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti PI-4 kinase 2A detects a band of approximately 54 kDa in Jurkat cell lysate
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin - Immunogen
- KLH-conjugated synthetic peptide corresponding to aa 387-415 of human PI-4 kinase 2A
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- Q9BTU6
- Entrez Gene
- PI4K2A
- GO Terms
- GO:0000287 magnesium ion binding
- GO:0004430 1-phosphatidylinositol 4-kinase activity
- GO:0005887 integral to plasma membrane
- GO:0005524 ATP binding
- GO:0005737 cytoplasm
- GO:0006661 phosphatidylinositol biosynthetic process
- GO:0045121 membrane raft
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- Regulatory
- For research purposes only
Applications of PI-4 Kinase 2A antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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