PI-3 Kinase p110 Subunit Delta antibody

Rabbit anti Human PI-3 Kinase p110 Subunit Delta (C-Terminal)

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
PI-3 Kinase p110 Subunit Delta
Region
(C-TERMINAL)

Product Code Applications Pack Size List Price Your Price Qty
AHP1805
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E WB 0.1 mg loader
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loader
Search for Batch Specific Datasheets

Rabbit anti Human PI-3 kinase subunit Delta recognizes an epitope within the C-terminal (CT) region of human PI3-kinase p110 subunit delta (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta), a member of the PI3/PI4-kinase family of lipid kinases, implicated in the regulation of signal transduction during cell growth.

PI3-kinase is a heterodimer consisting of a p85 regulatory subunit and a p110 catalytic subunit, which itself is divided into isoforms p110alpha, p110beta, p110delta and p110gamma.Expression of p110delta is predominantly restricted to leucocytes, exhibits a broad phosphoinositide lipid substrate specificity, and binds to Ras-GTP and p85.

Rabbit anti Human PI-3 kinase subunit Delta is suitable for use in immunocytochemistry.

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to p110 delta (CT) was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
<0.1% Sodium Azide (NaN3)
0.1% Bovine Serum Albumin
Immunogen
Synthetic peptide SWKTKVNWLAHNVSKDNRQ with added cysteine, corresponding to amino acids 1026-1044 within the C-terminal region of human PI3-Kinase p110 subunit delta.
Approx. Protein Concentrations
IgG concentration 1.0mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1/75000
Western Blotting 1/3000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
ELISA
This product is suitable for use in indirect ELISA applications.

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Synonyms
p110 Delta
RRID
AB_2165262
UniProt
O00329
Entrez Gene
PIK3CD
GO Terms
GO:0005886 plasma membrane
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005942 phosphatidylinositol 3-kinase complex
GO:0006468 protein phosphorylation
GO:0016303 1-phosphatidylinositol-3-kinase activity
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity
GO:0048015 phosphatidylinositol-mediated signaling
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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