Phospholipase C-GAMMA-2 antibody

Rabbit anti Phospholipase C-GAMMA-2

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
Phospholipase C-GAMMA-2

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AHP2510
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Rabbit anti phospholipase C-gamma-2 antibody recognizes phospholipase C-gamma-2 also known as PLCG2. Phospholipase C is a family of enzymes that cleave phospholipids producing molecules (DAG & IP3) that induce further downstream signaling.

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat Expected from Sequence
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to phospholipase C-gamma-2 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02% Sodium Azide
50% Glycerol
Immunogen
Recombinant human phospholipase C-gamma-2
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 1/50 1/200
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti phospholipase C-gamma-2 antibody detects a band of approximately 147 kDa in cell lysates under reducing conditions

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UniProt
P16885
Entrez Gene
PLCG2
GO Terms
GO:0005886 plasma membrane
GO:0005515 protein binding
GO:0004435 phosphatidylinositol phospholipase C activity
GO:0004871 signal transducer activity
GO:0009395 phospholipid catabolic process
GO:0030168 platelet activation
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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