Rabbit anti phospholipase C-gamma-1 antibody recognizes phospholipase C-gamma-1 also known as PLCG1. Phospholipase C is a family of enzymes that cleave phospholipids producing molecules (DAG & IP3) that induce further downstream signaling.
- Target Species
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to phospholipase C-gamma-1 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
- Synthetic human phospholipase C-gamma-1
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
calcium ion binding
phosphatidylinositol phospholipase C activity
receptor signaling protein activity
epidermal growth factor receptor signaling pathway
activation of phospholipase C activity
fibroblast growth factor receptor signaling pathway
phospholipid catabolic process
positive regulation of blood vessel endothelial cell migration
interspecies interaction between organisms
positive regulation of angiogenesis
nerve growth factor receptor signaling pathway
T cell receptor signaling pathway
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Phospholipase C-Gamma-1 antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti phospholipase C-gamma-1 antibody detects a band of approximately 149 kDa in cell lysates and tissue lysates under reducing conditions
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Secondary Antibodies Available
Useful Reagents Available