PHF6 antibody

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Anti PHF6 Antibody gallery image 1 — Western blot analysis was performed by loading 25µg of various whole cell lysates probed with Rabbit anti PHF6 (**AHP3007**) at 1/1000 dilution. Arrow points to PHF6 (molecular weight 41 kDa).

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Rabbit anti PHF6

Product Type: Polyclonal Antibody
Isotype: Polyclonal IgG
Specificity: PHF6

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Batch/Lot Specific Datasheets

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Product Code Applications Pack Size List Price Your Price Qty

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AHP3007 Datasheet Datasheet SDS SDS	WB	50 µl		Log in	Get Quote
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Rabbit anti PHF6 antibody recognizes PHD finger protein 6, also known as CENP-31, BFLS, BORJ and KIAA1823.

The gene encoding PHF6 is located on the x-chromosome, and mutations cause Borjeson-Forssman-Lehmann Syndrome, a rare disease characterized by features including intellectual disability, developmental delay, and epilepsy (Mangelsdorf et al. 2009). PHF6 is a tumor suppressor, and a negative regulator of hemopoietic stem cell (HSC) self-renewal (McRae et al. 2019). Therefore, mutations that inactivate PHF6 gene function have also been implicated in hematological malignancies (Miyagi et al. 2019).

Target Species: Human
Species Cross-Reactivity: Target Species Cross Reactivity

Mouse; N.B. Antibody reactivity and working conditions may vary between species.
Product Form: Purified IgG - liquid
Antiserum Preparation: Antiserum to PHF6 was raised by repeated immunization of rabbits with highly purified antigen
Buffer Solution: Phosphate buffered saline
Preservative Stabilisers: 0.02% Sodium Azide
50% Glycerol
Immunogen: Recombinant protein of human PHF6
Regulatory: For research purposes only
Guarantee: 12 months from date of despatch

Target Species	Cross Reactivity
Mouse

Store at -20^oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/500	1/2000

Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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UniProt: Q8IWS0
Entrez Gene: PHF6
GO Terms: GO:0005730 nucleolus; GO:0006350 transcription; GO:0008270 zinc ion binding; GO:0045449 regulation of transcription