PHF6 antibody

Rabbit anti PHF6

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
PHF6

Product Code Applications Pack Size List Price Your Price Qty
AHP3007
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 50 µl loader
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loader
Search for Batch Specific Datasheets

Rabbit anti PHF6 antibody recognizes PHD finger protein 6, also known as CENP-31, BFLS, BORJ and KIAA1823.

The gene encoding PHF6 is located on the x-chromosome, and mutations cause Borjeson-Forssman-Lehmann Syndrome, a rare disease characterized by features including intellectual disability, developmental delay, and epilepsy (Mangelsdorf et al. 2009). PHF6 is a tumor suppressor, and a negative regulator of hemopoietic stem cell (HSC) self-renewal (McRae et al. 2019). Therefore, mutations that inactivate PHF6 gene function have also been implicated in hematological malignancies (Miyagi et al. 2019).

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to PHF6 was raised by repeated immunization of rabbits with highly purified antigen
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02% Sodium Azide
50% Glycerol
Immunogen
Recombinant protein of human PHF6
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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UniProt
Q8IWS0
Entrez Gene
PHF6
GO Terms
GO:0005730 nucleolus
GO:0006350 transcription
GO:0008270 zinc ion binding
GO:0045449 regulation of transcription
Request a different product with this specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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