PGAM1 antibody
Goat anti Human PGAM1 antibody recognizes phosphoglycerate mutase 1 (PGAM1), also known as BPG-dependent PGAM 1, phosphoglycerate mutase isozyme B or PGAM-B.
Phosphoglycerate mutase 1 is widely distributed in mammalian tissues where it catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway (summary by Chen et al., 1974 (PubMed 4811757)) (supplied by OMIM, Nov 2010).
Goat anti Human PGAM1 antibody detects a band of 28 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Phosphoglycerate mutase 1 is widely distributed in mammalian tissues where it catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway (summary by Chen et al., 1974 (PubMed 4811757)) (supplied by OMIM, Nov 2010).
Goat anti Human PGAM1 antibody detects a band of 28 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti PGAM1 detects a band of approximately 28 kDa in Jurkat cell lysates.
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Goat polyclonal antibody purified by affinity chromatography.
- Buffer Solution
- TRIS buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide (NaN3) 0.5 % BSA
- Immunogen
- Peptide with the sequence C-KAMEAVAAQGKAKK, from the C Terminus of the protein sequence.
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P18669
- Entrez Gene
- PGAM1
- GO Terms
- GO:0004082 bisphosphoglycerate mutase activity
- GO:0004083 2,3-bisphospho-D-glycerate 2-phosphohydrolase activity
- GO:0004619 phosphoglycerate mutase activity
- GO:0005829 cytosol
- GO:0006094 gluconeogenesis
- GO:0006096 glycolysis
- GO:0006110 regulation of glycolysis
- GO:0019901 protein kinase binding
- GO:0043456 regulation of pentose-phosphate shunt
- GO:0045730 respiratory burst
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- Regulatory
- For research purposes only
Applications of PGAM1 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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