Peroxiredoxin 6 antibody

Rabbit anti Peroxiredoxin 6

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
Peroxiredoxin 6

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VPA00707
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Rabbit anti Human peroxiredoxin 6 antibody recognizes peroxiredoxin-6, also known as 1-Cys PRX, 1-Cys peroxiredoxin, acidic calcium-independent phospholipase A2, PRDX6, or non-selenium glutathione peroxidase.

The protein encoded by PRDX6 gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury (provided by RefSeq, Jul 2008).

Rabbit anti Human peroxiredoxin 6 antibody detects a band of 25 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Rabbit anti peroxiredoxin 6 detects a band of approximately 25 kDa in HeLa cell lysates.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography on Protein A.
Buffer Solution
HEPES buffered saline.
Preservative Stabilisers
0.09% Sodium Azide
1% Bovine Serum Albumin
<50% Glycerol
Immunogen
E. coli-derived recombinant human peroxiredoxin 6
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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UniProt
P30041
Entrez Gene
PRDX6
GO Terms
GO:0005515 protein binding
GO:0005764 lysosome
GO:0004623 phospholipase A2 activity
GO:0005829 cytosol
GO:0055114 oxidation-reduction process
GO:0045454 cell redox homeostasis
GO:0009395 phospholipid catabolic process
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0051920 peroxiredoxin activity
View more products with PEROXIREDOXIN specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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