Peroxiredoxin 5 antibody
Rabbit anti Human peroxiredoxin 5 antibody recognizes peroxiredoxin 5, mitochondrial, also known as Alu co-repressor 1, epididymis secretory protein Li 55, peroxisomal antioxidant enzyme or thioredoxin reductase.
PRDX5 gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. This protein interacts with peroxisome receptor 1. The crystal structure of this protein in its reduced form has been resolved to 1.5 angstrom resolution. PRDX5 uses alternate in-frame translation initiation sites to generate mitochondrial or peroxisomal/cytoplasmic forms. Three transcript variants encoding distinct isoforms have been identified for PRDX5 (provided by RefSeq, Jul 2008).
Rabbit anti Human peroxiredoxin 5 antibody detects a band of 17 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PRDX5 gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in different tissues under normal conditions and during inflammatory processes. This protein interacts with peroxisome receptor 1. The crystal structure of this protein in its reduced form has been resolved to 1.5 angstrom resolution. PRDX5 uses alternate in-frame translation initiation sites to generate mitochondrial or peroxisomal/cytoplasmic forms. Three transcript variants encoding distinct isoforms have been identified for PRDX5 (provided by RefSeq, Jul 2008).
Rabbit anti Human peroxiredoxin 5 antibody detects a band of 17 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Rabbit anti peroxiredoxin 5 detects a band of approximately 17 kDa in HeLa cell lysates
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
2% Sucrose - Immunogen
- Synthetic peptide encompassing part of the middle region of human peroxiredoxin 5
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P30044
- Entrez Gene
- PRDX5
- GO Terms
- GO:0005739 mitochondrion
- GO:0004601 peroxidase activity
- GO:0005777 peroxisome
- GO:0055114 oxidation-reduction process
- GO:0045454 cell redox homeostasis
- GO:0006954 inflammatory response
- GO:0034614 cellular response to reactive oxygen species
- GO:0043027 caspase inhibitor activity
- GO:0043066 negative regulation of apoptosis
- GO:0044445 cytosolic part
- GO:0051920 peroxiredoxin activity
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
- Regulatory
- For research purposes only
Applications of Peroxiredoxin 5 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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