PDGF-C antibody

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Anti PDGF-C Antibody (PrecisionAb Polyclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with PDGF-C antibody followed by detection with HRP conjugated Goat anti Rabbit (1/10,000, STAR208P) and visualized on the ChemiDoc MP with 11 second exposure. Arrow points to PDGF-C (molecular weight 45 kDa)

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Rabbit anti PDGF-C

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified
Specificity: PDGF-C

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VPA00287 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
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Rabbit anti Human PDGF-C antibody recognizes platelet derived growth factor C (PDGF-C), also known as VEGF-E, secretory growth factor-like protein and spinal cord-derived growth factor.

PDGF-C is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. PDGF-C appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for PDGFC (provided by RefSeq, Sep 2010).

Rabbit anti Human PDGF-C antibody detects a band of 45 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Anti PDGF-C detects a band of approximately 45 kDa in MCF7 cell lysate.
Product Form: Ig fraction - liquid
Preparation: Rabbit Ig fraction prepared by ammonium sulphate precipitation.
Buffer Solution: Phosphate buffered saline.
Preservative Stabilisers: 0.09% Sodium Azide (NaN₃).
Immunogen: KLH-conjugated synthetic peptide corresponding to aa 74-103 of human PDGF-C
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Rabbit IgG (H/L):HRP	STAR208P	WB	2 ml	Log in	Get Quote
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Description	Goat anti Rabbit IgG (H/L):HRP

UniProt: Q9NRA1
Entrez Gene: PDGFC
GO Terms: GO:0000139 Golgi membrane; GO:0005161 platelet-derived growth factor receptor binding; GO:0005615 extracellular space; GO:0005634 nucleus; GO:0005788 endoplasmic reticulum lumen; GO:0007417 central nervous system development; GO:0008083 growth factor activity; GO:0042803 protein homodimerization activity; GO:0043498 cell surface binding; View More GO Terms; GO:0045740 positive regulation of DNA replication; GO:0048008 platelet-derived growth factor receptor signaling pathway; GO:0048010 vascular endothelial growth factor receptor signaling pathway; GO:0048146 positive regulation of fibroblast proliferation; GO:0051781 positive regulation of cell division