PDGF-C antibody
Rabbit anti Human PDGF-C antibody recognizes platelet derived growth factor C (PDGF-C), also known as VEGF-E, secretory growth factor-like protein and spinal cord-derived growth factor.
PDGF-C is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. PDGF-C appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for PDGFC (provided by RefSeq, Sep 2010).
Rabbit anti Human PDGF-C antibody detects a band of 45 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PDGF-C is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. PDGF-C appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for PDGFC (provided by RefSeq, Sep 2010).
Rabbit anti Human PDGF-C antibody detects a band of 45 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti PDGF-C detects a band of approximately 45 kDa in MCF7 cell lysate
- Product Form
- Ig fraction - liquid
- Preparation
- Rabbit Ig fraction prepared by ammonium sulphate precipitation
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- KLH-conjugated synthetic peptide corresponding to aa 74-103 of human PDGF-C
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- Q9NRA1
- Entrez Gene
- PDGFC
- GO Terms
- GO:0000139 Golgi membrane
- GO:0005161 platelet-derived growth factor receptor binding
- GO:0005615 extracellular space
- GO:0005634 nucleus
- GO:0005788 endoplasmic reticulum lumen
- GO:0007417 central nervous system development
- GO:0008083 growth factor activity
- GO:0042803 protein homodimerization activity
- GO:0043498 cell surface binding
- GO:0045740 positive regulation of DNA replication
- GO:0048008 platelet-derived growth factor receptor signaling pathway
- GO:0048010 vascular endothelial growth factor receptor signaling pathway
- GO:0048146 positive regulation of fibroblast proliferation
- GO:0051781 positive regulation of cell division
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- Regulatory
- For research purposes only
Applications of PDGF-C antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
Copyright © 2020 Bio-Rad Antibodies (formerly AbD Serotec)
Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml |
