PDGF-C antibody

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Rabbit anti PDGF-C

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Product Code Applications Pack Size List Price Quantity
VPA00287
Datasheet
WB
MSDS
100 µl loader

Rabbit anti Human PDGF-C antibody recognizes platelet derived growth factor C (PDGF-C), also known as VEGF-E, secretory growth factor-like protein and spinal cord-derived growth factor.

PDGF-C is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. PDGF-C appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for PDGFC (provided by RefSeq, Sep 2010).

Rabbit anti Human PDGF-C antibody detects a band of 45 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Anti PDGF-C detects a band of approximately 45 kDa in MCF7 cell lysate
Product Form
Ig fraction - liquid
Preparation
Rabbit Ig fraction prepared by ammonium sulphate precipitation
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
KLH-conjugated synthetic peptide corresponding to aa 74-103 of human PDGF-C

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles
Guarantee
12 months from date of despatch

More Information

UniProt
Q9NRA1
Entrez Gene
PDGFC
GO Terms
GO:0000139 Golgi membrane
GO:0005161 platelet-derived growth factor receptor binding
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005788 endoplasmic reticulum lumen
GO:0007417 central nervous system development
GO:0008083 growth factor activity
GO:0042803 protein homodimerization activity
GO:0043498 cell surface binding
GO:0045740 positive regulation of DNA replication
GO:0048008 platelet-derived growth factor receptor signaling pathway
GO:0048010 vascular endothelial growth factor receptor signaling pathway
GO:0048146 positive regulation of fibroblast proliferation
GO:0051781 positive regulation of cell division
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory
For research purposes only

Applications of PDGF-C antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rabbit IgG (H/L):HRP STAR208P WB 2 ml