Rabbit anti PAK2 antibody recognizes PAK2 also known as p21 protein (Cdc42/Rac)-activated kinase 2. PAK2 is a member of the p21 activated kinases (PAK) which act downstream of Rho GTPases. PAKs are involved in regulation of the cytoskeleton and nuclear signaling.
- Target Species
- Species Cross-Reactivity
|Target Species||Cross Reactivity|
||Expected from Sequence
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to PAK2 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
- Recombinant human PAK2
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
protein serine/threonine kinase activity
negative regulation of protein kinase activity
cellular component disassembly involved in apoptosis
identical protein binding
regulation of apoptosis
protein kinase binding
protein tyrosine kinase activator activity
T cell costimulation
regulation of growth
interspecies interaction between organisms
perinuclear region of cytoplasm
regulation of defense response to virus by virus
positive regulation of peptidyl-tyrosine phosphorylation
T cell receptor signaling pathway
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of PAK2 antibody
|Immunohistology - Paraffin
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti PAK2 antibody detects a band of approximately 65 kDa in Jurkat cell lysate and mouse tissue lysates under reducing conditions
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Secondary Antibodies Available
Useful Reagents Available