OP18 antibody

Rabbit anti OP18

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
OP18

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VPA00882
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Rabbit anti Human Op18 antibody recognizes the oncoprotein 18, also known as STMN1, leukemia-associated phosphoprotein p18, metablastin, prosolin and stathmin.

STMN1 belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for STMN1 (provided by RefSeq, Feb 2009).

Rabbit anti Human Op18 antibody detects a band of 19 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti Op18 antibody recognizes a band of approximately 19 kDa in Jurkat cell lysates
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography on immunogen
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
Immunogen
Synthetic peptide corresponding to a portion of the N terminal segment of human Op18
Regulatory
For research purposes only
Guarantee
12 months from date of despatch
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories

Store undiluted at -20°C, avoiding repeated freeze thaw cycles

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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UniProt
P16949
Entrez Gene
STMN1
GO Terms
GO:0009615 response to virus
GO:0004871 signal transducer activity
GO:0035556 intracellular signal transduction
GO:0005737 cytoplasm
GO:0005874 microtubule
GO:0007019 microtubule depolymerization
GO:0007052 mitotic spindle organization
GO:0007399 nervous system development
GO:0015631 tubulin binding
GO:0030154 cell differentiation
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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