OP18 antibody
Rabbit anti Human Op18 antibody recognizes the oncoprotein 18, also known as STMN1, leukemia-associated phosphoprotein p18, metablastin, prosolin and stathmin.
STMN1 belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for STMN1 (provided by RefSeq, Feb 2009).
Rabbit anti Human Op18 antibody detects a band of 19 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
STMN1 belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for STMN1 (provided by RefSeq, Feb 2009).
Rabbit anti Human Op18 antibody detects a band of 19 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti Op18 antibody recognizes a band of approximately 19 kDa in Jurkat cell lysates
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography on immunogen
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
- Immunogen
- Synthetic peptide corresponding to a portion of the N terminal segment of human Op18
Storage Information
- Storage
- Store undiluted at -20°C, avoiding repeated freeze thaw cycles
- Guarantee
- As supplied, 12 months from date of despatch
More Information
- UniProt
- P16949 Related reagents
- Entrez Gene
- STMN1 Related reagents
- GO Terms
- GO:0009615 response to virus
- GO:0004871 signal transducer activity
- GO:0035556 intracellular signal transduction
- GO:0005737 cytoplasm
- GO:0005874 microtubule
- GO:0007019 microtubule depolymerization
- GO:0007052 mitotic spindle organization
- GO:0007399 nervous system development
- GO:0015631 tubulin binding
- GO:0030154 cell differentiation
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
- Regulatory
- For research purposes only
Applications of OP18 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml |
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