Ocil antibody

Goat anti Ocil

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
Ocil

Product Code Applications Pack Size List Price Your Price Qty
AHP3010
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 0.1 mg
List Price Your Price
Search for Batch Specific Datasheets

Goat anti Human OCIL antibody recognizes c-type lectin domain family 2 member D, also known as CLC2D, CLAX, and LLT1.

Originally described as an osteoblast-derived inhibitory factor of osteoclasts (Zhou et al.. 2001), OCIL is a member of the C-type lectin-like receptor superfamily (CTLR). OCIL is expressed on lymphocytes including B cells, NK cells, T cells, and activated dendritic cells. At the cell surface, OCIL acts as a ligand for the NKRP1A receptor (CD161), which contributes to differentiation of lymphocytes (Marrufo et al.. 2018). Interaction between OCIL and CD161 appears to actively participate in the anti-tumoral immune response, and have both been suggested as targets for immunotherapy strategies to enhance immune responses (Braud et al.. 2018). The suggestion of OCIL as a target for immunotherapy has been strengthened by the finding that it is expressed in a variety of healthy tissues and in immune-privileged sites (Llibre et al.. 2016).

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antisera to human OCIL were raised by repeated immunizations of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer Solution
TRIS buffered saline
Preservative Stabilisers
0.02% Sodium Azide
0.5% Bovine Serum Albumin
Immunogen
Peptide with sequence C-LLRYKGPSDH, from the Internal region of the protein sequence according to NP_037401.1; NP_001004419.1; NP_001184246.1.
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20°C only.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 3 µg/ml 0.5 µg/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Goat anti Human OCIL antibody detects a band of approximately 30 to 35 kDa in cell lysates.

Description Product Code Applications Pack Size List Price Your Price Quantity
Rabbit anti Goat IgG (Fc):FITC STAR122F F 1 mg loader
List Price Your Price
loader
Description Rabbit anti Goat IgG (Fc):FITC
Rabbit anti Goat IgG (Fc):HRP STAR122P C E WB 1 mg loader
List Price Your Price
loader
Description Rabbit anti Goat IgG (Fc):HRP
Request a different product with this specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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