Ocil antibody

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Anti Ocil Antibody gallery image 1 — Western blot analysis of U937 cell lysate (35 μg protein in RIPA buffer) probed with Goat anti Human OCIL antibody (0.3 μg/ml, **AHP3010**) and detected by chemiluminescence.

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Goat anti Ocil

Product Type: Polyclonal Antibody
Isotype: Polyclonal IgG
Specificity: Ocil

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AHP3010 Datasheet Datasheet SDS SDS	WB	0.1 mg		Log in	Get Quote
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Goat anti Human OCIL antibody recognizes c-type lectin domain family 2 member D, also known as CLC2D, CLAX, and LLT1.

Originally described as an osteoblast-derived inhibitory factor of osteoclasts (Zhou et al.. 2001), OCIL is a member of the C-type lectin-like receptor superfamily (CTLR). OCIL is expressed on lymphocytes including B cells, NK cells, T cells, and activated dendritic cells. At the cell surface, OCIL acts as a ligand for the NKRP1A receptor (CD161), which contributes to differentiation of lymphocytes (Marrufo et al.. 2018). Interaction between OCIL and CD161 appears to actively participate in the anti-tumoral immune response, and have both been suggested as targets for immunotherapy strategies to enhance immune responses (Braud et al.. 2018). The suggestion of OCIL as a target for immunotherapy has been strengthened by the finding that it is expressed in a variety of healthy tissues and in immune-privileged sites (Llibre et al.. 2016).

Target Species: Human
Product Form: Purified IgG - liquid
Antiserum Preparation: Antisera to human OCIL were raised by repeated immunizations of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer Solution: TRIS buffered saline
Preservative Stabilisers: 0.02% Sodium Azide
0.5% Bovine Serum Albumin
Immunogen: Peptide with sequence C-LLRYKGPSDH, from the Internal region of the protein sequence according to NP_037401.1; NP_001004419.1; NP_001184246.1.
Approx. Protein Concentrations: IgG concentration 0.5 mg/ml
Regulatory: For research purposes only
Guarantee: 12 months from date of despatch

Store at -20°C only.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		3 µg/ml	0.5 µg/ml

Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Western Blotting: Goat anti Human OCIL antibody detects a band of approximately 30 to 35 kDa in cell lysates.

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