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Goat anti Ocil
- Product Type
- Polyclonal Antibody
- Polyclonal IgG
|Goat anti Human OCIL antibody recognizes c-type lectin domain family 2 member D, also known as CLC2D, CLAX, and LLT1.
Originally described as an osteoblast-derived inhibitory factor of osteoclasts (Zhou et al.. 2001), OCIL is a member of the C-type lectin-like receptor superfamily (CTLR). OCIL is expressed on lymphocytes including B cells, NK cells, T cells, and activated dendritic cells. At the cell surface, OCIL acts as a ligand for the NKRP1A receptor (CD161), which contributes to differentiation of lymphocytes (Marrufo et al.. 2018). Interaction between OCIL and CD161 appears to actively participate in the anti-tumoral immune response, and have both been suggested as targets for immunotherapy strategies to enhance immune responses (Braud et al.. 2018). The suggestion of OCIL as a target for immunotherapy has been strengthened by the finding that it is expressed in a variety of healthy tissues and in immune-privileged sites (Llibre et al.. 2016).
- Target Species
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antisera to human OCIL were raised by repeated immunizations of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
- Buffer Solution
- TRIS buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
0.5% Bovine Serum Albumin
- Peptide with sequence C-LLRYKGPSDH, from the Internal region of the protein sequence according to NP_037401.1; NP_001004419.1; NP_001184246.1.
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
- For research purposes only
- 12 months from date of despatch
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
|Application Name||Verified||Min Dilution||Max Dilution|
|Western Blotting||3 µg/ml||0.5 µg/ml|
- Western Blotting
- Goat anti Human OCIL antibody detects a band of approximately 30 to 35 kDa in cell lysates.
|Description||Product Code||Applications||Pack Size||List Price||Your Price||Quantity|
|Rabbit anti Goat IgG (Fc):FITC||STAR122F||F||1 mg||Log in|
|List Price||Your Price|
|Description||Rabbit anti Goat IgG (Fc):FITC|
|Rabbit anti Goat IgG (Fc):HRP||STAR122P||C E WB||1 mg||Log in|
|List Price||Your Price|
|Description||Rabbit anti Goat IgG (Fc):HRP|
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