Nucleoside Diphosphate Kinase A antibody

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Anti Nucleoside Diphosphate Kinase A Antibody (PrecisionAb Polyclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with Goat anti Human nucleoside diphosphate kinase A antibody (**VPA00517**) followed by detection with Donkey anti Sheep/Goat IgG (Fc):HRP (1/10,000, STAR88P) and visualized on the ChemiDoc MP with 6 second exposure. Arrow points to nucleoside diphosphate kinase A (molecular weight 16 kDa).

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Goat anti Nucleoside Diphosphate Kinase A

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified
Specificity: Nucleoside Diphosphate Kinase A

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VPA00517 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
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Goat anti Human nucleoside diphosphate kinase A antibody recognizes nucleoside diphosphate kinase A, also known as NDP kinase A, granzyme A-activated DNase, metastasis inhibition factor nm23, NM23-H1 or tumor metastatic process-associated protein.

The NME1 gene was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by NME2) isoforms. Mutations in NME1 have been identified in aggressive neuroblastomas (Chang et al. 1994). Two transcript variants encoding different isoforms have been found for NME1. Co-transcription of NME1 and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product (provided by RefSeq, Jul 2008).

Goat anti Human nucleoside diphosphate kinase A antibody detects a band of 16 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Anti nucleoside diphosphate kinase A detects a band of approximately 16 kDa in HEK293 cell lysates.
Species Cross-Reactivity: Target Species Cross Reactivity

Mouse

Rat; N.B. Antibody reactivity and working conditions may vary between species.
Product Form: Purified IgG - liquid.
Preparation: Goat polyclonal antibody purified by affinity chromatography.
Buffer Solution: TRIS buffered saline.
Preservative Stabilisers: 0.09% Sodium Azide (NaN₃)
0.5% Bovine Serum Albumin.
Immunogen: Peptide sequence DYTSCAQNWIYE
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Target Species	Cross Reactivity
Mouse
Rat

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Donkey anti Sheep/Goat IgG:HRP	STAR88P	C E P WB	1 ml	Log in	Get Quote
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Description	Donkey anti Sheep/Goat IgG:HRP

UniProt: P15531
Entrez Gene: NME1
GO Terms: GO:0000287 magnesium ion binding; GO:0004536 deoxyribonuclease activity; GO:0004550 nucleoside diphosphate kinase activity; GO:0005829 cytosol; GO:0005524 ATP binding; GO:0005525 GTP binding; GO:0005634 nucleus; GO:0006183 GTP biosynthetic process; GO:0006228 UTP biosynthetic process; View More GO Terms; GO:0006241 CTP biosynthetic process; GO:0006897 endocytosis; GO:0007399 nervous system development; GO:0008285 negative regulation of cell proliferation; GO:0042802 identical protein binding; GO:0015949 nucleobase, nucleoside and nucleotide interconversion; GO:0042981 regulation of apoptosis; GO:0030154 cell differentiation; GO:0043388 positive regulation of DNA binding; GO:0050679 positive regulation of epithelial cell proliferation