NFAT4 antibody

Rabbit anti NFAT4

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
NFAT4

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VPA00901
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Rabbit anti Human NFAT4 antibody recognizes NFAT4, also known as NF-ATc3, nuclear factor of activated T-cells-cytoplasmic 3, T cell transcription factor NFAT4 and nuclear factor of activated T-cells c3 isoform IE-Xa.

The product of NFATC3 is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of NFATC3 plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for NFATC3 (provided by RefSeq, Nov 2010).

Rabbit anti Human NFAT4 antibody detects bands of 140-190 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti NFAT4 antibody recognizes a band of approximately 140-190 kDa in Ramos cell lysates
Species Cross-Reactivity
Target SpeciesCross Reactivity
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography on immunogen
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
<50% Glycerol
Immunogen
Recombinant protein of human NFAT4
Regulatory
For research purposes only
Guarantee
12 months from date of despatch
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories

Store undiluted at -20°C, avoiding repeated freeze thaw cycles

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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UniProt
Q12968
Entrez Gene
NFATC3
GO Terms
GO:0005886 plasma membrane
GO:0003677 DNA binding
GO:0005737 cytoplasm
GO:0005730 nucleolus
GO:0006366 transcription from RNA polymerase II promoter
GO:0006954 inflammatory response
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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