Myh antibody
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WB ResetRabbit anti Myh
- Product Type
- PrecisionAb Polyclonal
- Isotype
- Polyclonal IgG
- Format
- Purified
- Specificity
- Myh
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| Rabbit anti Human MYH antibody recognizes the A/G-specific adenine DNA glycosylase. The MUTYH gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in MUTYH result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for MUTYH (provided by RefSeq, Jul 2008). Rabbit anti Human MYH antibody detects a band of 55 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
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- Target Species
- Human
- Western Blotting
- Rabbit anti MYH detects a band of approximately 55 kDa in K562 cell lysates.
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography.
- Buffer Solution
- TRIS buffered glycine.
- Preservative Stabilisers
- 0.01% Thiomersal
<50% Glycerol - Immunogen
- Recombinant protein encompassing part of the middle region of human MYH
- Regulatory
- For research purposes only.
- Guarantee
- 12 months from date of despatch.
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml | Log in | |||
| List Price | Your Price | ||||||
| Log in | |||||||
| Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
- UniProt
- Q9UIF7
- Entrez Gene
- MUTYH
- GO Terms
- GO:0004519 endonuclease activity
- GO:0046872 metal ion binding
- GO:0005654 nucleoplasm
- GO:0006298 mismatch repair
- GO:0019104 DNA N-glycosylase activity
- GO:0032407 MutSalpha complex binding
- GO:0045007 depurination
- GO:0051539 4 iron, 4 sulfur cluster binding
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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