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MTA1L1 antibody

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Western Blot Validated
Anti MTA1L1 Antibody (PrecisionAb Polyclonal Antibody) gallery image 1
Western blot analysis of whole cell lysates probed with MTA1L1 antibody followed by detection with HRP conjugated Goat anti Rabbit IgG (1/10,000, STAR208P) and visualized on the ChemiDoc MP with 2 second exposure. Arrow points to MTA1L1 (molecular weight 75 kDa)

Rabbit anti MTA1L1

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
PrecisionAb Antibodies
Product Code Applications Pack Size List Price Quantity
VPA00092
Datasheet
WB
MSDS
100 µl loader

Rabbit anti Human MTA1L1 antibody recognizes human metastasis-associated protein 1-like 1 (MTA1L1), also known as MTA2, a subunit of the nucleosome remodelling and deacetylating complex (NURD) (Yao and Yang, 2003). MTA1L1 specifically interacts with p53 and reduces the levels of acetylated p53, represses p53-dependent transcriptional activation and modulates p53-mediated cell growth arrest and apoptosis (Luo et al. 2000).

Rabbit anti Human MTA1L1 antibody detects metastasis-associated protein 1-like 1 as a band of 75 kDa in a wide range of human cell line lysates. Cross reactivity with rodent cell lines is also observed.

Product Details

Target Species
Human
Western Blotting
Rabbit anti MTA1L1 detects a band of approximately 75 kDa in Jurkat cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
A peptide corresponding to amino acids 652-688 of human MTA1L1.

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
Guarantee
As supplied, 12 months from date of despatch.

More Information

UniProt
O94776 Related reagents
Entrez Gene
MTA2 Related reagents
GO Terms
GO:0005515 protein binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0006333 chromatin assembly or disassembly
GO:0008270 zinc ion binding
GO:0016581 NuRD complex
GO:0043565 sequence-specific DNA binding
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory
For research purposes only

Applications of MTA1L1 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
Copyright © 2019 Bio-Rad Antibodies (formerly AbD Serotec)

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rabbit IgG (H/L):HRP STAR208P WB 2 ml

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