MTA1L1 antibody

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Anti MTA1L1 Antibody (PrecisionAb Polyclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with MTA1L1 antibody followed by detection with HRP conjugated Goat anti Rabbit IgG (1/10,000, STAR208P) and visualized on the ChemiDoc MP with 2 second exposure. Arrow points to MTA1L1 (molecular weight 75 kDa).

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Rabbit anti MTA1L1

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified
Specificity: MTA1L1

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VPA00092 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
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Rabbit anti Human MTA1L1 antibody recognizes human metastasis-associated protein 1-like 1 (MTA1L1), also known as MTA2, a subunit of the nucleosome remodelling and deacetylating complex (NURD) (Yao and Yang, 2003). MTA1L1 interacts with p53 and reduces the levels of acetylated p53, represses p53-dependent transcriptional activation and modulates p53-mediated cell growth arrest and apoptosis (Luo et al. 2000).

Rabbit anti Human MTA1L1 antibody detects metastasis-associated protein 1-like 1 as a band of 75 kDa in a wide range of human cell line lysates. Cross reactivity with rodent cell lines is also observed.

Target Species: Human
Western Blotting: Rabbit anti MTA1L1 detects a band of approximately 75 kDa in Jurkat cell lysates.
Species Cross-Reactivity: Target Species Cross Reactivity

Mouse

Rat; N.B. Antibody reactivity and working conditions may vary between species.
Product Form: Purified IgG - liquid
Preparation: Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution: Phosphate buffered saline.
Preservative Stabilisers: 0.09% Sodium Azide (NaN₃).
Immunogen: A peptide corresponding to amino acids 652-688 of human MTA1L1.
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Target Species	Cross Reactivity
Mouse
Rat

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting			1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Rabbit IgG (H/L):HRP	STAR208P	WB	2 ml	Log in	Get Quote
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Description	Goat anti Rabbit IgG (H/L):HRP

Synonyms: MTA2
UniProt: O94776
Entrez Gene: MTA2
GO Terms: GO:0005515 protein binding; GO:0003700 sequence-specific DNA binding transcription factor activity; GO:0006333 chromatin assembly or disassembly; GO:0008270 zinc ion binding; GO:0016581 NuRD complex; GO:0043565 sequence-specific DNA binding