MTA1L1 antibody
Rabbit anti Human MTA1L1 antibody recognizes human metastasis-associated protein 1-like 1 (MTA1L1), also known as MTA2, a subunit of the nucleosome remodelling and deacetylating complex (NURD) (Yao and Yang, 2003). MTA1L1 specifically interacts with p53 and reduces the levels of acetylated p53, represses p53-dependent transcriptional activation and modulates p53-mediated cell growth arrest and apoptosis (Luo et al. 2000).
Rabbit anti Human MTA1L1 antibody detects metastasis-associated protein 1-like 1 as a band of 75 kDa in a wide range of human cell line lysates. Cross reactivity with rodent cell lines is also observed.
Rabbit anti Human MTA1L1 antibody detects metastasis-associated protein 1-like 1 as a band of 75 kDa in a wide range of human cell line lysates. Cross reactivity with rodent cell lines is also observed.
Product Details
- Target Species
- Human
- Western Blotting
- Rabbit anti MTA1L1 detects a band of approximately 75 kDa in Jurkat cell lysates.
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- A peptide corresponding to amino acids 652-688 of human MTA1L1.
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- O94776
- Entrez Gene
- MTA2
- GO Terms
- GO:0005515 protein binding
- GO:0003700 sequence-specific DNA binding transcription factor activity
- GO:0006333 chromatin assembly or disassembly
- GO:0008270 zinc ion binding
- GO:0016581 NuRD complex
- GO:0043565 sequence-specific DNA binding
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- Regulatory
- For research purposes only
Applications of MTA1L1 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml |
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