MTA1L1 antibody

Rabbit anti MTA1L1

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
MTA1L1

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VPA00092
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Rabbit anti Human MTA1L1 antibody recognizes human metastasis-associated protein 1-like 1 (MTA1L1), also known as MTA2, a subunit of the nucleosome remodelling and deacetylating complex (NURD) (Yao and Yang, 2003). MTA1L1 interacts with p53 and reduces the levels of acetylated p53, represses p53-dependent transcriptional activation and modulates p53-mediated cell growth arrest and apoptosis (Luo et al. 2000).

Rabbit anti Human MTA1L1 antibody detects metastasis-associated protein 1-like 1 as a band of 75 kDa in a wide range of human cell line lysates. Cross reactivity with rodent cell lines is also observed.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Rabbit anti MTA1L1 detects a band of approximately 75 kDa in Jurkat cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
Immunogen
A peptide corresponding to amino acids 652-688 of human MTA1L1.
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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Synonyms
MTA2
UniProt
O94776
Entrez Gene
MTA2
GO Terms
GO:0005515 protein binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0006333 chromatin assembly or disassembly
GO:0008270 zinc ion binding
GO:0016581 NuRD complex
GO:0043565 sequence-specific DNA binding
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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