MMP-2 antibody
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WB P ResetRabbit anti MMP-2
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- MMP-2
Antibody Quality and Performance Guarantee
| Rabbit anti MMP-2 antibody recognizes 72 kDa type IV collagenase, also known as 72 kDa gelatinase, gelatinase A, MMP-2 and TBE-1. It belongs to the matrix metalloproteinases (MMPs) family (McCawley and Matrisian 2001) related to zinc-dependent endopeptidases of Metzicin family (Mannello and Medda 2012). MMPs are produced and assembled in the cytoplasm as proenzymes (Xie et al. 2017). The expression of MMP2 has been associated with poor prognosis in brain neoplasms (Jaalinoja et al. 2000), ovarian carcinoma (Davidson et al. 1999) and lung carcinoma (Kodate et al. 1997). |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to MMP-2 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
50% Glycerol - Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 40-280 of human MMP-2
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunohistology - Paraffin |  |
1/50 | 1/200 |
| Western Blotting | |
1/500 | 1/10000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti MMP-2 antibody detects a band of approximately 70 kDa in U-87MG and A375 cell lysates and mouse liver tissue under reducing conditions
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
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| Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
| Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
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| Description | Sheep anti Rabbit IgG:RPE | ||||||
| Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
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| List Price | Your Price | ||||||
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| Description | Goat anti Rabbit IgG (Fc):Biotin | ||||||
| Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
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| List Price | Your Price | ||||||
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| Description | Goat anti Rabbit IgG (Fc):FITC | ||||||
| Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
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| List Price | Your Price | ||||||
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| Description | Sheep anti Rabbit IgG:FITC | ||||||
| Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
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| List Price | Your Price | ||||||
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| Description | Goat anti Rabbit IgG (Fc):HRP | ||||||
- UniProt
- P08253
- Entrez Gene
- MMP2
- GO Terms
- GO:0005515 protein binding
- GO:0001525 angiogenesis
- GO:0004222 metalloendopeptidase activity
- GO:0005578 proteinaceous extracellular matrix
- GO:0005615 extracellular space
- GO:0005634 nucleus
- GO:0006508 proteolysis
- GO:0008270 zinc ion binding
- GO:0030574 collagen catabolic process
- View More GO Terms
AHP2735
148747
150436
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
View more products with MMP-2 specificity
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