MIF antibody

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Goat anti MIF

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified

Product Code	Applications	Pack Size	Your Price	List Price	Quantity
VPA00057 Datasheet	WB SDS	100 µl	Log in		Get Quote

Goat anti Human MIF antibody recognizes MIF, also known as macrophage migration inhibitory factor. In humans, the MIF protein is encoded by the MIF gene. This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways.

Goat anti Human MIF antibody detects MIF as a single band of 13 kDa in a wide range of human cell line lysates.

Product Details

Target Species: Human
Western Blotting: Goat anti MIF detects a band of approximately 13 kDa in Jurkat cell lysates.
Product Form: Purified IgG - liquid
Preparation: Goat polyclonal antibody purified by affinity chromatography
Buffer Solution: TRIS buffered saline
Preservative Stabilisers: 0.02% Sodium Azide (NaN₃)
0.5% Bovine Serum Albumin
Immunogen: Peptide with sequence C-NAANVGWNNSTFA from the C terminus of the protein sequence.

Storage Information

Storage: Store undiluted at -20^oC, avoiding repeated freeze thaw cycles.
Guarantee: 12 months from date of despatch

More Information

UniProt: P14174
Entrez Gene: MIF
GO Terms: GO:0001516 prostaglandin biosynthetic process; GO:0004167 dopachrome isomerase activity; GO:0005125 cytokine activity; GO:0005126 cytokine receptor binding; GO:0005615 extracellular space; GO:0005737 cytoplasm; GO:0006954 inflammatory response; GO:0007166 cell surface receptor linked signaling pathway; GO:0008283 cell proliferation; GO:0009986 cell surface; GO:0010629 negative regulation of gene expression; GO:0010739 positive regulation of protein kinase A signaling cascade; GO:0030890 positive regulation of B cell proliferation; GO:0033138 positive regulation of peptidyl-serine phosphorylation; GO:0042056 chemoattractant activity; GO:0043030 regulation of macrophage activation; GO:0043066 negative regulation of apoptosis; GO:0043498 cell surface binding; GO:0043518 negative regulation of DNA damage response, signal transduction by p53 class mediator; GO:0045087 innate immune response; GO:0048146 positive regulation of fibroblast proliferation; GO:0050178 phenylpyruvate tautomerase activity; GO:0050715 positive regulation of cytokine secretion; GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation; GO:0070207 protein homotrimerization; GO:0070374 positive regulation of ERK1 and ERK2 cascade; GO:0071157 negative regulation of cell cycle arrest
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory: For research purposes only

Applications of MIF antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting			1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description	Product Code	Applications	Pack Size	Your Price	List Price	Quantity
Donkey anti Sheep/Goat IgG:HRP	STAR88P	C E P WB	1 ml	Log in		Get Quote

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