Rabbit anti MEK 6 (pSer207) antibody
recognizes MAPK/ERK kinase 6 (MEK 6), also known as dual specificity mitogen-activated protein kinase kinase 6, MAP kinase kinase 6 (MAPKK 6) and stress-activated protein kinase kinase 3, when phosphorylated at serine 207.
MEK 6 is a dual specificity protein kinase and a member of the MAP kinase family. MEK 6 plays a key role in the p38 MAP kinase signaling pathway. MEK 6 is regulated by phosphorylation at serine 207 (Zanke et al. 1996
- Target Species
- Species Cross-Reactivity
|Target Species||Cross Reactivity|
||Expected from Sequence
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to MEK 6 (pSer207) was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
- Phospho specific-peptide corresponding to residues surrounding serine 207 of human MEK 6
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
activation of MAPK activity
MyD88-dependent toll-like receptor signaling pathway
MyD88-independent toll-like receptor signaling pathway
protein serine/threonine kinase activity
MAP kinase kinase activity
protein tyrosine kinase activity
DNA damage induced protein phosphorylation
cell cycle arrest
Toll signaling pathway
toll-like receptor 1 signaling pathway
toll-like receptor 2 signaling pathway
toll-like receptor 3 signaling pathway
toll-like receptor 4 signaling pathway
muscle cell differentiation
innate immune response
positive regulation of muscle cell differentiation
stress-activated MAPK cascade
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of MEK 6 (pSer207) antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Copyright © 2020 Bio-Rad Antibodies (formerly AbD Serotec)
Secondary Antibodies Available
Useful Reagents Available
Product Specific References
Zanke, B.W. et al. (1996) Mammalian mitogen-activated protein kinase pathways are regulated through formation of specific kinase-activator complexes.
J Biol Chem. 271 (47): 29876-81.