MEK 6 (pSer207) antibody
Filter by Application:
WB ResetRabbit anti MEK 6 (pSer207)
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- MEK 6 (pSer207)
Antibody Quality and Performance Guarantee
| Rabbit anti MEK 6 (pSer207) antibody recognizes MAPK/ERK kinase 6 (MEK 6), also known as dual specificity mitogen-activated protein kinase kinase 6, MAP kinase kinase 6 (MAPKK 6) and stress-activated protein kinase kinase 3, when phosphorylated at serine 207. MEK 6 is a dual specificity protein kinase and a member of the MAP kinase family. MEK 6 plays a key role in the p38 MAP kinase signaling pathway. MEK 6 is regulated by phosphorylation at serine 207 (Zanke et al. 1996). |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Rat Expected from Sequence - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to MEK 6 (pSer207) was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
50% Glycerol - Immunogen
- Phospho specific-peptide corresponding to residues surrounding serine 207 of human MEK 6
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/500 | 1/1000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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Further Reading
-
Zanke, B.W. et al. (1996) Mammalian mitogen-activated protein kinase pathways are regulated through formation of specific kinase-activator complexes.
J Biol Chem. 271 (47): 29876-81.
- UniProt
- P52564
- Entrez Gene
- MAP2K6
- GO Terms
- GO:0000187 activation of MAPK activity
- GO:0005515 protein binding
- GO:0002755 MyD88-dependent toll-like receptor signaling pathway
- GO:0002756 MyD88-independent toll-like receptor signaling pathway
- GO:0005829 cytosol
- GO:0004674 protein serine/threonine kinase activity
- GO:0004708 MAP kinase kinase activity
- GO:0004713 protein tyrosine kinase activity
- GO:0005524 ATP binding
- View More GO Terms
- GO:0005654 nucleoplasm
- GO:0006975 DNA damage induced protein phosphorylation
- GO:0007050 cell cycle arrest
- GO:0008063 Toll signaling pathway
- GO:0034130 toll-like receptor 1 signaling pathway
- GO:0034134 toll-like receptor 2 signaling pathway
- GO:0034138 toll-like receptor 3 signaling pathway
- GO:0034142 toll-like receptor 4 signaling pathway
- GO:0042692 muscle cell differentiation
- GO:0045087 innate immune response
- GO:0051149 positive regulation of muscle cell differentiation
- GO:0051403 stress-activated MAPK cascade
AHP2654
141611
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