Rabbit anti MAX (pSer11) antibody
recognizes MAX, also known as protein max, class D basic helix-loop-helix protein 4, bHLHd4 or Myc-associated factor X, when phosphorylated at serine 11. MAX is a member of the basic-helix-loop-helix leucine zipper (bHLHZip) transcription factor (TF) family. MAX is a binding partner for Myc and Mad proteins and through dimerization with these TFs regulates transcription.
MAX is phosphorylated at serine 11 by casein kinase II (CK2) (Krippner-Heidenreich et al. 2001
- Target Species
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to MAX (pSer11) was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
- Phospho specific-peptide corresponding to residues surrounding serine 11 of human MAX
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
sequence-specific DNA binding transcription factor activity
transcription coactivator activity
transcription from RNA polymerase II promoter
transcription regulator activity
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of MAX (pSer11) antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Copyright © 2021 Bio-Rad Antibodies (formerly AbD Serotec)
Secondary Antibodies Available
Useful Reagents Available
Product Specific References
Krippner-Heidenreich, A. et al. (2001) Targeting of the transcription factor Max during apoptosis: phosphorylation-regulated cleavage by caspase-5 at an unusual glutamic acid residue in position P1.
Biochem J. 358 (Pt 3): 705-15.
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