MAX (pSer11) antibody

Rabbit anti MAX (pSer11)

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
MAX (pSer11)

Product Code Applications Pack Size List Price Your Price Qty
AHP2647
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 50 µl loader
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loader
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Rabbit anti MAX (pSer11) antibody recognizes MAX, also known as protein max, class D basic helix-loop-helix protein 4, bHLHd4 or Myc-associated factor X, when phosphorylated at serine 11. MAX is a member of the basic-helix-loop-helix leucine zipper (bHLHZip) transcription factor (TF) family. MAX is a binding partner for Myc and Mad proteins and through dimerization with these TFs regulates transcription.

MAX is phosphorylated at serine 11 by casein kinase II (CK2) (Krippner-Heidenreich et al. 2001).

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to MAX (pSer11) was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02% Sodium Azide
50% Glycerol
Immunogen
Phospho specific-peptide corresponding to residues surrounding serine 11 of human MAX
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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Further Reading

  1. Krippner-Heidenreich, A. et al. (2001) Targeting of the transcription factor Max during apoptosis: phosphorylation-regulated cleavage by caspase-5 at an unusual glutamic acid residue in position P1.
    Biochem J. 358 (Pt 3): 705-15.

UniProt
P61244
Entrez Gene
MAX
GO Terms
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003713 transcription coactivator activity
GO:0005737 cytoplasm
GO:0006366 transcription from RNA polymerase II promoter
GO:0030528 transcription regulator activity
GO:0071339 MLL1 complex
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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