Rabbit anti MAPK8 / JNK1 antibody recognizes a region surrounding amino acid 412 of mitogen activated protein kinase-8 (MAPK8) also known as JNK-46, stress-activated protein kinase 1c and stress-activated protein kinase JNK1. MAPK8 is a member of a pathway which is activated by inflammatory cytokines such as THF-α and IL-1.
- Target Species
- Species Cross-Reactivity
|Target Species||Cross Reactivity|
||Expected from Sequence
||Expected from Sequence
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 30% Glycerol
0.5% Bovine Serum Albumin
- Synthetic peptide surrounding amino acid 412 of human MAPK8
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
MyD88-dependent toll-like receptor signaling pathway
MyD88-independent toll-like receptor signaling pathway
JUN kinase activity
Toll signaling pathway
induction of apoptosis by intracellular signals
activation of pro-apoptotic gene products
response to UV
toll-like receptor 1 signaling pathway
toll-like receptor 2 signaling pathway
toll-like receptor 3 signaling pathway
toll-like receptor 4 signaling pathway
negative regulation of apoptosis
innate immune response
nerve growth factor receptor signaling pathway
regulation of transcription factor activity
stress-activated MAPK cascade
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of MAPK8 / JNK1 antibody
|Immunohistology - Paraffin
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti MAPK8 antibody recognizes a doublet between 50 and 65 kDa in Jurkat cell lysates
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Secondary Antibodies Available