M3K11 antibody
Rabbit anti M3K11 antibody recognizes a region close to the carboxy terminus of human Mitogen-activated protein kinase kinase kinase 11 also known as M3K11, Mixed lineage kinase 3, MLK3 or Src-homology 3 domain-containing proline-rich kinase. M3K11 is a serine/threonine kinase involved in the p38 stress pathway. It may also have a role in the immune and inflammatory response when stimulated by CD3/CD28.
Product Details
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Expected from Sequence Rat Expected from Sequence - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 50% Glycerol
1% Bovine Serum Albumin
0.02% Thiomersal - Immunogen
- Synthetic peptide mapping to the C-terminus of human M3K11
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
Storage Information
- Storage
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- Q16584
- Entrez Gene
- MAP3K11
- GO Terms
- GO:0000080 G1 phase of mitotic cell cycle
- GO:0004706 JUN kinase kinase kinase activity
- GO:0005524 ATP binding
- GO:0005813 centrosome
- GO:0005874 microtubule
- GO:0007017 microtubule-based process
- GO:0007257 activation of JUN kinase activity
- GO:0008283 cell proliferation
- GO:0042803 protein homodimerization activity
- GO:0046777 protein autophosphorylation
- GO:0051259 protein oligomerization
- Regulatory
- For research purposes only
Applications of M3K11 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 0.5 | 4.0 ug/ml |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti M3K11 antibody recognizes a band of approximately 92 kDa in HeLa lysates
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
|
|
| Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
|
|
| Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
|
|
| Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
|
|
| Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
|
|
| Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
|
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