Rabbit anti M3K11 antibody recognizes a region close to the carboxy terminus of human Mitogen-activated protein kinase kinase kinase 11 also known as M3K11, Mixed lineage kinase 3, MLK3 or Src-homology 3 domain-containing proline-rich kinase. M3K11 is a serine/threonine kinase involved in the p38 stress pathway. It may also have a role in the immune and inflammatory response when stimulated by CD3/CD28.
- Target Species
- Species Cross-Reactivity
|Target Species||Cross Reactivity|
||Expected from Sequence
||Expected from Sequence
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 50% Glycerol
1% Bovine Serum Albumin
- Synthetic peptide mapping to the C-terminus of human M3K11
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
G1 phase of mitotic cell cycle
JUN kinase kinase kinase activity
activation of JUN kinase activity
protein homodimerization activity
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of M3K11 antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti M3K11 antibody recognizes a band of approximately 92 kDa in HeLa lysates
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Secondary Antibodies Available
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