Lysine-Specific Histone Demethylase antibody

Rabbit anti Lysine-Specific Histone Demethylase
- Product Type
- PrecisionAb Polyclonal
- Isotype
- Polyclonal IgG
- Format
- Purified
- Specificity
- Lysine-Specific Histone Demethylase
Rabbit anti Human lysine-specific histone demethylase antibody recognizes lysine-specific histone demethylase (LSD1), a ubiquitously expressed nuclear protein belonging to the flavin monoamine oxidase family and containing a single SWIRM domain. Histone modifications mediate changes in gene expression by altering chromatin structure or by serving as a platform to recruit other proteins. LSD1 is an amine oxidase that catalyzes the lysine-specific demethylation of histone proteins via an FAD-dependent oxidative reaction. Methylation on histone H3-K9 is thought to play an important role in heterochromatin formation, while methylation on arginine and some lysine residues, e.g. H3-K4, are associated with active transcription. Rabbit anti Human lysine-specific histone demethylase antibody recognizes a band of ~115 kDa in multiple cell lines by western blotting under reducing conditions. This antibody is expected to recognize both described isoforms of lysine-specific histone demethylase. |
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- Target Species
- Human
- Western Blotting
- Anti lysine-specific histone demethylase antibody detects a band of approximately 115 kDa in Jurkat cell lysates.
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline.
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3).
- Immunogen
- Peptide corresponding corresponding to a 17 amino acid sequence from the N-terminus of human LSD1
- Regulatory
- For research purposes only.
- Guarantee
- 12 months from date of despatch.
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Western Blotting | ![]() |
1/1000 |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml | Log in | |||
List Price | Your Price | ||||||
Log in | |||||||
Description | Goat anti Rabbit IgG (H/L):HRP |
VPA00009

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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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