Lyn antibody

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Rabbit anti Lyn

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified

Product Code	Applications	Pack Size	Your Price	List Price	Quantity
VPA00605 Datasheet	WB SDS	100 µl	Log in		Get Quote

Rabbit anti Human Lyn antibody recognizes the tyrosine-protein kinase Lyn, also known as lck/Yes-related novel protein tyrosine kinase, v-yes-1 or Yamaguchi sarcoma viral related oncogene homolog.

The LYN gene encodes a tyrosine protein kinase, which maybe involved in the regulation of mast cell degranulation, and erythroid differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for LYN (provided by RefSeq, Jul 2011).

Rabbit anti Human Lyn antibody detects bands of 53 and 56 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species

Human

Western Blotting

Rabbit anti Lyn detects bands of approximately 53 and 56 kDa in Ramos cell lysates.

Species Cross-Reactivity

Target Species	Cross Reactivity
Mouse

N.B. Antibody reactivity and working conditions may vary between species.

Product Form

Purified IgG - liquid.

Preparation

Rabbit polyclonal antibody purified by affinity chromatography.

Buffer Solution

Phosphate buffered saline.

Preservative Stabilisers

0.09% Sodium Azide.

Immunogen

KLH conjugated synthetic peptide between amino acids 43 - 77 of human Lyn

Storage Information

Storage: Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
Guarantee: 12 months from date of despatch

More Information

UniProt: P07948
Entrez Gene: LYN
GO Terms: GO:0005886 plasma membrane; GO:0005515 protein binding; GO:0005829 cytosol; GO:0004715 non-membrane spanning protein tyrosine kinase activity; GO:0004716 receptor signaling protein tyrosine kinase activity; GO:0005524 ATP binding; GO:0005634 nucleus; GO:0005794 Golgi apparatus; GO:0006468 protein phosphorylation; GO:0006974 response to DNA damage stimulus; GO:0008284 positive regulation of cell proliferation; GO:0009725 response to hormone stimulus; GO:0030168 platelet activation; GO:0030218 erythrocyte differentiation; GO:0031295 T cell costimulation; GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein; GO:0044419 interspecies interaction between organisms; GO:0045121 membrane raft; GO:0048471 perinuclear region of cytoplasm; GO:0050900 leukocyte migration; GO:0051272 positive regulation of cellular component movement; GO:0070304 positive regulation of stress-activated protein kinase signaling cascade
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories
Regulatory: For research purposes only.

Applications of Lyn antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting			1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description	Product Code	Applications	Pack Size	Your Price	List Price	Quantity
Goat anti Rabbit IgG (H/L):HRP	STAR208P	WB	2 ml	Log in		Get Quote

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