Rabbit anti Lyn antibody
recognizes Lyn, also known as LYN proto-oncogene or JTK8. Lyn is a member of the Src family of protein tyrosine kinases. Lyn plays a vital role in myeloid differentiation (Harder et al. 2001
- Target Species
- Species Cross-Reactivity
|Target Species||Cross Reactivity|
||Expected from Sequence
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to Lyn was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
- Recombinant human Lyn
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
non-membrane spanning protein tyrosine kinase activity
receptor signaling protein tyrosine kinase activity
response to DNA damage stimulus
positive regulation of cell proliferation
response to hormone stimulus
T cell costimulation
positive regulation of tyrosine phosphorylation of STAT protein
interspecies interaction between organisms
perinuclear region of cytoplasm
positive regulation of cellular component movement
positive regulation of stress-activated protein kinase signaling cascade
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Lyn antibody
|Immunohistology - Paraffin
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti Lyn antibody detects a band of approximately 59 kDa in A431 cell lysates and mouse tissue lysates under reducing conditions
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Secondary Antibodies Available
Useful Reagents Available