Lymphotoxin Beta Receptor antibody

Rabbit anti Lymphotoxin Beta Receptor

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
Lymphotoxin Beta Receptor

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VPA00869
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Rabbit anti Human lymphotoxin beta receptor antibody recognizes the lymphotoxin beta receptor, also known as lymphotoxin B receptor, tumor necrosis factor C receptor, tumor necrosis factor receptor 2-related protein and tumor necrosis factor receptor superfamily member 3.

LTBR encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed (provided by RefSeq, Aug 2012).

Rabbit anti Human lymphotoxin beta receptor antibody detects a band of 50 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti lymphotoxin beta receptor antibody recognizes a band of approximately 50 kDa in SNU-423 cell lysates
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography on immunogen
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
2% Sucrose
Immunogen
Synthetic peptide corresponding to a portion of the C terminal segment of human lymphotoxin beta receptor
Regulatory
For research purposes only
Guarantee
12 months from date of despatch
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories

Store undiluted at -20°C, avoiding repeated freeze thaw cycles

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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UniProt
P36941
Entrez Gene
LTBR
GO Terms
GO:0005515 protein binding
GO:0006915 apoptosis
GO:0016021 integral to membrane
GO:0004872 receptor activity
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0044419 interspecies interaction between organisms