Lactate Dehydrogenase 5 antibody
Sheep anti Human Lactate Dehydrogenase 5
- Product Type
- Polyclonal Antibody
- Polyclonal IgG
- Lactate Dehydrogenase 5
|Sheep anti lactate dehydrogenase 5 antibody reacts with LDH2-5, and exhibits low reactivity with LDH1. L-lactate dehydrogenase isozymes exist as tetramers of two subunits with LDH-1 composed for 4 β chains and LDH-5 composed of 4 α chains. LDH-2 =3β:1α, LDH-3 = 2β:2α, LDH-4 = 1β:3α (Boyer et al. 1963).
Mutations in the LDHA gene can lead to the development of glycogen storage disease 11 (GSD11), a condition typified by myogloinurea, fatigue and pain.
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein G
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Native, highly purified lactate dehydrogenase 5.
- Approx. Protein Concentrations
- IgG concentration 5.0 mg/ml
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
Markert, C.L. (1963) Lactate Dehydrogenase Isozymes: Dissociation and Recombination of Subunits.
Science. 140 (3573): 1329-30.
Augoff, K. et al. (2015) Lactate dehydrogenase 5: an old friend and a new hope in the war on cancer.
Cancer Lett. 358 (1): 1-7.
Boyer, S.H. et al. (1963) Lactate dehydrogenase variant from human blood: evidence for molecular subunits.
Science. 141 (3581): 642-3.
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