Sheep anti Human Kappa Light Chain antibody detects human kappa immunoglobulin light chain, which comprises approximately 60% of light chains in humans.
Immunohistochemical detection of immunoglobulins is useful in determining the lymphoid origin of tissues and in the assessment of lymphoid proliferations as reactive or malignant. The assessment of light chain status is particularly important in this regard as it may be used to demonstrate the clonal nature of a tumour.
- Target Species
- Product Form
- Ig fraction - liquid
- Ig fraction prepared by sodium sulphate precipitation
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Purified human kappa light chains.
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
complement activation, classical pathway
innate immune response
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Kappa Light Chain antibody
|Immunohistology - Frozen
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.
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Secondary Antibodies Available