Rabbit anti IRF8 antibody recognizes IRF8, also known as interferon regulatory factor 8, interferon consensus sequence-binding protein and ICSBP. IRF8 is a member of the interferon regulatory factor (IRF) family of transcription factors. IRF family proteins bind to the specific sequnce known as interferon-stimulated response element (ISRE).
- Target Species
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to IRF8 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
- Recombinant human IRF8
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
negative regulation of transcription from RNA polymerase II promoter
sequence-specific enhancer binding RNA polymerase II transcription factor activity
interferon-gamma-mediated signaling pathway
type I interferon-mediated signaling pathway
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of IRF8 antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti IRF8 antibody detects a band of approximately 50 kDa in cell lysates and tissue lysates under reducing conditions
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Secondary Antibodies Available
Useful Reagents Available