IRF8 antibody

Rabbit anti IRF8

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
IRF8

Product Code Applications Pack Size List Price Your Price Qty
AHP2485
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 50 µl loader
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loader
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Rabbit anti IRF8 antibody recognizes IRF8, also known as interferon regulatory factor 8, interferon consensus sequence-binding protein and ICSBP. IRF8 is a member of the interferon regulatory factor (IRF) family of transcription factors. IRF family proteins bind to the specific sequnce known as interferon-stimulated response element (ISRE).

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to IRF8 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02% Sodium Azide
50% Glycerol
Immunogen
Recombinant human IRF8
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti IRF8 antibody detects a band of approximately 50 kDa in cell lysates and tissue lysates under reducing conditions

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UniProt
Q02556
Entrez Gene
IRF8
GO Terms
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0003677 DNA binding
GO:0003705 sequence-specific enhancer binding RNA polymerase II transcription factor activity
GO:0005634 nucleus
GO:0006955 immune response
GO:0060333 interferon-gamma-mediated signaling pathway
GO:0060337 type I interferon-mediated signaling pathway
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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