Rabbit anti IRF3 antibody recognizes human IRF3, also known as interferon regulatory factor 3.
Interferon regulatory factor 3 (IRF3) is a member of the IRF transcription factor family. IRF3 plays a role the immune response to viral infection.
- Target Species
- Species Cross-Reactivity
|Target Species||Cross Reactivity|
||Expected from Sequence
||Expected from Sequence
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to IRF3 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
- Synthetic human IRF3 peptide
- Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
MyD88-independent toll-like receptor signaling pathway
sequence-specific DNA binding transcription factor activity
RNA polymerase II transcription factor activity
transcription cofactor activity
response to virus
regulation of transcription, DNA-dependent
transcription from RNA polymerase II promoter
Toll signaling pathway
negative regulation of type I interferon production
toll-like receptor 3 signaling pathway
toll-like receptor 4 signaling pathway
interspecies interaction between organisms
innate immune response
interferon-gamma-mediated signaling pathway
type I interferon-mediated signaling pathway
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of IRF3 antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Rabbit anti IRF3 peptide antibody detects a band of approximately 49 kDa in tissue lysates under reducing conditions
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Secondary Antibodies Available
Useful Reagents Available