IRE1p antibody


Product Details
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Rat Mouse - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antisera to IRE1p were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
0.02% Sodium Azide (NaN3) - Immunogen
- A 16 amino acid peptide near the carboxy terminus of human IRE1p.
- Approx. Protein Concentrations
- IgG concentration 1.0mg/ml
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- O75460
- Entrez Gene
- ERN1
- GO Terms
- GO:0005515 protein binding
- GO:0000287 magnesium ion binding
- GO:0006915 apoptosis
- GO:0004674 protein serine/threonine kinase activity
- GO:0005524 ATP binding
- GO:0006350 transcription
- GO:0006397 mRNA processing
- GO:0006917 induction of apoptosis
- GO:0006987 activation of signaling protein activity involved in unfolded protein response
- GO:0007050 cell cycle arrest
- GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters
- GO:0030176 integral to endoplasmic reticulum membrane
- GO:0045449 regulation of transcription
- Regulatory
- For research purposes only
Applications of IRE1p antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Immunohistology - Frozen | |||
Western Blotting | 1 | 2ug/ml |
- Western Blotting
- AHP1012 detects a band of approximately 110kDa in A-20 cell lysate.
Secondary Antibodies Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
![]() |
|
Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
![]() |
|
Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
![]() |
|
Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
![]() |
|
Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
![]() |
|
Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
![]() |
|
Sheep anti Rabbit IgG:DyLight®488 | STAR36D488GA | F IF WB | 0.1 mg | ||
Sheep anti Rabbit IgG:DyLight®680 | STAR36D680GA | F IF WB | 0.1 mg | ||
Sheep anti Rabbit IgG:Dylight®800 | STAR36D800GA | F IF WB | 0.1 mg |
Useful Reagents Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
TidyBlot Western Blot Detection Reagent:HRP | STAR209P | WB* | 0.5 ml |
Product Specific References
Further Reading
-
Zhang, K. & Kaufman, R.J. (2004) Signaling the unfolded protein response from the endoplasmic reticulum.
J Biol Chem. 279 (25): 25935-8. -
Schröder, M. et al. (2003) IRE1- and HAC1-independent transcriptional regulation in the unfolded protein response of yeast.
Mol Microbiol. 49 (3): 591-606. -
Tirasophon, W. et al. (1998) A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells.
Genes Dev. 12 (12): 1812-24.
Fluorescent Spectraviewer
Watch the Tool Tutorial Video ▸
How to Use the Spectraviewer?
Watch the Tool Tutorial Video ▸
- Start by selecting the application you are interested in, with the option to select an instrument from the drop down menu or create a customized instrument
- Select the fluorophores or fluorescent proteins you want to include in your panel to check compatibility
- Select the lasers and filters you wish to include
- Select combined or multi-laser view to visualize the spectra