IRAK4 antibody

Rabbit anti IRAK4

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
IRAK4

Product Code Applications Pack Size List Price Your Price Qty
AHP2482
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 50 µl loader
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loader

Rabbit anti IRAK4 antibody recognizes human IRAK4, also known as interleukin-1 receptor associated kinase-like 4. IRAK4 unlike IRAK1-3 lacks the C-terminal domain required for TRAF6 interaction.

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse Expected from Sequence
Rat Expected from Sequence
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to IRAK4 was raised by repeated immunization of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02% Sodium Azide
50% Glycerol
Immunogen
Recombinant human IRAK4
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Store at -20oC
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/500 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
Rabbit anti IRAK4 antibody detects a band of approximately 55 kDa in cell lysates under reducing conditions

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UniProt
Q9NWZ3
Entrez Gene
IRAK4
GO Terms
GO:0005886 plasma membrane
GO:0000287 magnesium ion binding
GO:0002755 MyD88-dependent toll-like receptor signaling pathway
GO:0005829 cytosol
GO:0004674 protein serine/threonine kinase activity
GO:0005524 ATP binding
GO:0006468 protein phosphorylation
GO:0008063 Toll signaling pathway
GO:0010008 endosome membrane
GO:0034130 toll-like receptor 1 signaling pathway
GO:0034134 toll-like receptor 2 signaling pathway
GO:0034142 toll-like receptor 4 signaling pathway
GO:0045087 innate immune response

AHP2482

151346 158301

If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.

View more products with IRAK specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Human Products