IRAK2 antibody

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Anti IRAK2 Antibody (PrecisionAb Polyclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with Rabbit anti Human IRAK2 antibody (**VPA00134**) followed by detection with HRP conjugated Goat anti Rabbit IgG (1/10,000, STAR208P) and visualized on the ChemiDoc MP with 10 second exposure. Arrow points to IRAK2 (molecular weight 69 kDa).

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Rabbit anti IRAK2

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified
Specificity: IRAK2

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Product Code Applications Pack Size List Price Your Price Qty

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VPA00134 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
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Rabbit anti Human IRAK2 antibody recognizes interleukin-1 receptor-associated kinase-like 2 (IRAK2).

IRAK2 is one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL-1R) upon stimulation and is reported to participate in the IL-1-induced upregulation of NF-kappaB (provided by RefSeq, Jul 2008).

Rabbit anti Human IRAK2 antibody detects a band of 69 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Anti IRAK2 detects a band of approximately 69 kDa in HEK293 cell lysates.
Species Cross-Reactivity: Target Species Cross Reactivity

Rat; N.B. Antibody reactivity and working conditions may vary between species.
Product Form: Purified IgG - liquid
Preparation: Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution: Phosphate buffered saline.
Preservative Stabilisers: 0.02% Sodium Azide (NaN₃).
Immunogen: Peptide corresponding to amino acids near the carboxy terminus of human IRAK2.
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Target Species	Cross Reactivity
Rat

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting			1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Rabbit IgG (H/L):HRP	STAR208P	WB	2 ml	Log in	Get Quote
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Description	Goat anti Rabbit IgG (H/L):HRP

UniProt: O43187
Entrez Gene: IRAK2
GO Terms: GO:0005886 plasma membrane; GO:0000187 activation of MAPK activity; GO:0001959 regulation of cytokine-mediated signaling pathway; GO:0002755 MyD88-dependent toll-like receptor signaling pathway; GO:0002756 MyD88-independent toll-like receptor signaling pathway; GO:0005829 cytosol; GO:0004704 NF-kappaB-inducing kinase activity; GO:0005524 ATP binding; GO:0006954 inflammatory response; View More GO Terms; GO:0007249 I-kappaB kinase/NF-kappaB cascade; GO:0007254 JNK cascade; GO:0008063 Toll signaling pathway; GO:0009986 cell surface; GO:0010008 endosome membrane; GO:0032088 negative regulation of NF-kappaB transcription factor activity; GO:0034130 toll-like receptor 1 signaling pathway; GO:0034134 toll-like receptor 2 signaling pathway; GO:0034138 toll-like receptor 3 signaling pathway; GO:0034142 toll-like receptor 4 signaling pathway; GO:0042803 protein homodimerization activity; GO:0045087 innate immune response; GO:0046982 protein heterodimerization activity; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0051403 stress-activated MAPK cascade; GO:0070498 interleukin-1-mediated signaling pathway; GO:0070555 response to interleukin-1