IRAK2 antibody

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Rabbit anti IRAK2

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified

Product Code	Applications	Pack Size	Your Price	List Price	Quantity
VPA00134 Datasheet	WB SDS	100 µl	Log in		Get Quote

Rabbit anti Human IRAK2 antibody recognizes interleukin-1 receptor-associated kinase-like 2 (IRAK2).

IRAK2 is one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL-1R) upon stimulation and is reported to participate in the IL-1-induced upregulation of NF-kappaB (provided by RefSeq, Jul 2008).

Rabbit anti Human IRAK2 antibody detects a band of 69 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species

Human

Western Blotting

Anti IRAK2 detects a band of approximately 69 kDa in HEK293 cell lysates.

Species Cross-Reactivity

Target Species	Cross Reactivity
Rat

N.B. Antibody reactivity and working conditions may vary between species.

Product Form

Purified IgG - liquid

Preparation

Rabbit polyclonal antibody purified by affinity chromatography.

Buffer Solution

Phosphate buffered saline

Preservative Stabilisers

0.02% Sodium Azide (NaN₃)

Immunogen

Peptide corresponding to amino acids near the carboxy terminus of human IRAK2.

Storage Information

Storage: Store undiluted at -20^oC, avoiding repeated freeze thaw cycles.
Guarantee: 12 months from date of despatch

More Information

UniProt: O43187
Entrez Gene: IRAK2
GO Terms: GO:0005886 plasma membrane; GO:0000187 activation of MAPK activity; GO:0001959 regulation of cytokine-mediated signaling pathway; GO:0002755 MyD88-dependent toll-like receptor signaling pathway; GO:0002756 MyD88-independent toll-like receptor signaling pathway; GO:0005829 cytosol; GO:0004704 NF-kappaB-inducing kinase activity; GO:0005524 ATP binding; GO:0006954 inflammatory response; GO:0007249 I-kappaB kinase/NF-kappaB cascade; GO:0007254 JNK cascade; GO:0008063 Toll signaling pathway; GO:0009986 cell surface; GO:0010008 endosome membrane; GO:0032088 negative regulation of NF-kappaB transcription factor activity; GO:0034130 toll-like receptor 1 signaling pathway; GO:0034134 toll-like receptor 2 signaling pathway; GO:0034138 toll-like receptor 3 signaling pathway; GO:0034142 toll-like receptor 4 signaling pathway; GO:0042803 protein homodimerization activity; GO:0045087 innate immune response; GO:0046982 protein heterodimerization activity; GO:0051092 positive regulation of NF-kappaB transcription factor activity; GO:0051403 stress-activated MAPK cascade; GO:0070498 interleukin-1-mediated signaling pathway; GO:0070555 response to interleukin-1
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.
Regulatory: For research purposes only

Applications of IRAK2 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting			1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description	Product Code	Applications	Pack Size	Your Price	List Price	Quantity
Goat anti Rabbit IgG (H/L):HRP	STAR208P	WB	2 ml	Log in		Get Quote

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