ILP-2 antibody

Rabbit anti ILP-2

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
ILP-2

Product Code Applications Pack Size List Price Your Price Qty
AHP731
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SDS Safety Datasheet SDS
WB 0.1 mg loader
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loader
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Rabbit anti ILP-2 antibody recognizes Baculoviral IAP repeat-containing protein 8 also known as inhibitor of apoptosis protein- like protein 2 ,ILP-2 or BIRC8. ILP-2 is a 236 amino acid ~27 kDa cytoplasmic protein belonging to the IAP family of apoptosis inhibitors and is expressed solely in the testis in normal tissue.

ILP-2 is reported to bind to caspase 9 (Richter et al. 2001) and is thought to protect against apoptosis mediated by BAX (Kim et al. 2011).

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Rat Expected from Sequence
Mouse Expected from Sequence
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Antiserum Preparation
Antisera to human ILP-2 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.02%Sodium Azide
Immunogen
Synthetic peptide TGYEARLITFGT corresponding to amino acids 2-13 of human ILP-2.
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1ug/ml 2ug/ml
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
Western Blotting
AHP731 detects a band of approximately 33kDa in HepG2 and MOLT4 cell lysates.

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Further Reading

  1. Richter, B.W. et al. (2001) Molecular cloning of ILP-2, a novel member of the inhibitor of apoptosis protein family.
    Mol Cell Biol. 21 (13): 4292-301.

Synonyms
BIRC8
RRID
AB_2064493
UniProt
Q96P09
Entrez Gene
BIRC8
GO Terms
GO:0006915 apoptosis
GO:0008270 zinc ion binding
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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