Rabbit anti Human interleukin-36 gamma antibody,
recognizes interleukin-36 gamma (IL-36 gamma) also known as IL-1 related protein 2, IL-1 epsilon, IL-1 family member 9 and IL-1 homologue 1.
IL-36 gamma is a member of the IL-1 superfamily of cytokines and elicits its biological function through the IL-1 receptor-related protein 2. Activation of this receptor can lead to the activation of the NF-κB, MAPK, JNK and ERK signaling cascades (Bao et al. 2020
). In this way, IL-36 gamma is able to act as a proinflammatory cytokine, with the exact biological function dependent on the type and site of inflammation (Ding et al. 2017
- Target Species
- Product Form
- Purified IgG - lyophilized
- Reconstitute with 0.1 ml distilled water
- Antiserum Preparation
- Produced from sera of rabbits immunized with recombinant human interleukin-36 gamma and purified by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present
- Carrier Free
- E. coli derived recombinant human interleukin-36 gamma
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml after reconstitution
- Endotoxin Level
- < 0.1 ng/μg of protein (< 1 EU/μg)
- Prior to reconstitution store at -20°C.
After reconstitution store at -20°C.
This product should be stored undiluted. Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
interleukin-1 receptor antagonist activity
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of IL-36 Gamma antibody
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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Secondary Antibodies Available
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