IL-22 Receptor antibody

Goat anti Human Interleukin-22 Receptor (N-Terminal)

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Specificity
IL-22 Receptor
Region
(N-TERMINAL)

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AHP1820
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E IF P 0.1 mg loader
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Goat anti Human Interleukin-22 Receptor (N-Terminal) antibody specifically recognizes an epitope within the N-terminal (NT) region of human interleukin-22 receptor (IL-22R), also known as IL-22R alpha-1 (IL22RA1), a member of the type II cytokine receptor family, which signals via the JAK-STAT signalling pathway.

IL-22R acts as the functional receptor for IL-22, through association with the beta chain of the IL-10R, and as a receptor for IL-20 and IL-24 through association with the beta chain of IL-20R. Binding of IL-22 to functional IL-22R can be blocked by a soluble form of the receptor known as IL22 binding protein (IL22BP).

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to human IL-22R (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.1% Sodium Azide (NaN3)
Immunogen
Synthetic peptide DSGPEGTPDTVYSIEYKTYGERDWVAKKG corresponding to amino acids 42-70 within the N-terminal region of human IL-22 receptor.
Approx. Protein Concentrations
IgG concentration 1.0 mg/ml
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1/50000
Immunofluorescence 1/100
Immunohistology - Paraffin 1/150
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Histology Positive Control Tissue
Spleen or tonsil

Description Product Code Applications Pack Size List Price Your Price Quantity
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Description Rabbit anti Goat IgG (Fc):HRP

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Antigen Retrieval Buffer, pH8.0 BUF025A P 500 ml
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Description Antigen Retrieval Buffer, pH8.0

Synonyms
IL22RA1
RRID
AB_2295893
UniProt
Q8N6P7
Entrez Gene
IL22RA1
GO Terms
GO:0007596 blood coagulation
GO:0016021 integral to membrane
GO:0004904 interferon receptor activity
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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