IL-22 Receptor antibody
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P ResetGoat anti Human Interleukin-22 Receptor (N-Terminal)
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- IL-22 Receptor
- Region
- (N-TERMINAL)
Antibody Quality and 
Unrivaled 
| Goat anti Human Interleukin-22 Receptor (N-Terminal) antibody specifically recognizes an epitope within the N-terminal (NT) region of human interleukin-22 receptor (IL-22R), also known as IL-22R alpha-1 (IL22RA1), a member of the type II cytokine receptor family, which signals via the JAK-STAT signalling pathway. IL-22R acts as the functional receptor for IL-22, through association with the beta chain of the IL-10R, and as a receptor for IL-20 and IL-24 through association with the beta chain of IL-20R. Binding of IL-22 to functional IL-22R can be blocked by a soluble form of the receptor known as IL22 binding protein (IL22BP). |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antiserum to human IL-22R (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
- Immunogen
- Synthetic peptide DSGPEGTPDTVYSIEYKTYGERDWVAKKG corresponding to amino acids 42-70 within the N-terminal region of human IL-22 receptor.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
1/50000 | |
| Immunofluorescence | |
1/100 | |
| Immunohistology - Paraffin | |
1/150 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Histology Positive Control Tissue
- Spleen or tonsil
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| Description | Antigen Retrieval Buffer, pH8.0 | ||||||
- Synonyms
- IL22RA1
- RRID
- AB_2295893
- UniProt
- Q8N6P7
- Entrez Gene
- IL22RA1
- GO Terms
- GO:0007596 blood coagulation
- GO:0016021 integral to membrane
- GO:0004904 interferon receptor activity
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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