IGF2BP-3 antibody
Rabbit anti IGF2BP-3
- Product Type
- PrecisionAb Polyclonal
- Isotype
- Polyclonal IgG
- Format
- Purified
- Specificity
- IGF2BP-3
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| Rabbit anti Human IGF2BP-3 antibody recognizes insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP-3), also known as IMP3, KH domain containing protein overexpressed in cancer, VICKZ3 and CT98. IGF2BP-3 is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. This protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes (provided by RefSeq, Jul 2008). Rabbit anti Human IGF2BP-3 antibody detects a band of 69 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
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- Target Species
- Human
- Western Blotting
- Anti IGF2BP-3 detects a band of approximately 69 kDa in K562 cell lysate.
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline.
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
2% Sucrose - Immunogen
- Synthetic peptide corresponding to the central region of human IGF2BP-3
- Regulatory
- For research purposes only.
- Guarantee
- 12 months from date of despatch.
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
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| Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml | Log in | |||
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| Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
- UniProt
- O00425
- Entrez Gene
- IGF2BP3
- GO Terms
- GO:0000166 nucleotide binding
- GO:0005515 protein binding
- GO:0003730 mRNA 3'-UTR binding
- GO:0005829 cytosol
- GO:0005634 nucleus
- GO:0006412 translation
- GO:0009653 anatomical structure morphogenesis
- GO:0017148 negative regulation of translation
- GO:0042035 regulation of cytokine biosynthetic process
- View More GO Terms
- GO:0045182 translation regulator activity
- GO:0048027 mRNA 5'-UTR binding
View more products with IGF2BP-3 specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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