IGF2BP-1 antibody

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Anti IGF2BP-1 Antibody (PrecisionAb Polyclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with IGF2BP-1 antibody followed by detection with HRP conjugated Goat anti Rabbit (1/10,000, STAR208P) and visualized on the ChemiDoc MP with 12 second exposure. Arrow points to IGF2BP-1 (molecular weight 63 kDa)

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Rabbit anti IGF2BP-1

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified
Specificity: IGF2BP-1

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VPA00313 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
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Rabbit anti Human IGF2BP-1 antibody recognizes insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP-1), also known as IGF-II mRNA-binding protein 1, VICKZ family member 1, coding region determinant-binding protein and zipcode-binding protein 1.

Encoded by the IGF2BP1 gene, insulin-like growth factor 2 mRNA-binding protein 1 contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for IGF2BP1 (provided by RefSeq, May 2009).

Rabbit anti Human IGF2BP-1 antibody detects a band of 63 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Anti IGF2BP-1 detects a band of approximately 63 kDa in K562 cell lysate.
Species Cross-Reactivity: Target Species Cross Reactivity

Mouse; N.B. Antibody reactivity and working conditions may vary between species.
Product Form: Purified IgG - liquid
Preparation: Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution: Phosphate buffered saline.
Preservative Stabilisers: 0.09% Sodium Azide (NaN₃).
Immunogen: KLH-conjugated synthetic peptide corresponding to aa 508-534 of human IGF2BP-1
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Target Species	Cross Reactivity
Mouse

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Rabbit IgG (H/L):HRP	STAR208P	WB	2 ml	Log in	Get Quote
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Description	Goat anti Rabbit IgG (H/L):HRP

UniProt: Q9NZI8
Entrez Gene: IGF2BP1
GO Terms: GO:0005886 plasma membrane; GO:0000166 nucleotide binding; GO:0005515 protein binding; GO:0003730 mRNA 3'-UTR binding; GO:0005829 cytosol; GO:0005634 nucleus; GO:0010494 stress granule; GO:0010610 regulation of mRNA stability involved in response to stress; GO:0017148 negative regulation of translation; View More GO Terms; GO:0030027 lamellipodium; GO:0042035 regulation of cytokine biosynthetic process; GO:0043197 dendritic spine; GO:0045182 translation regulator activity; GO:0048027 mRNA 5'-UTR binding; GO:0070934 CRD-mediated mRNA stabilization; GO:0070937 CRD-mediated mRNA stability complex