Hrs / HGS antibody

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Goat anti Hrs / HGS

Goat anti-human HRS/HGS antibody recognizes hepatocyte growth factor-regulated tyrosine kinase substrate, also known as protein PP110. This antibody has been extensively validated for western blotting using whole cell lysates.

Hrs / HGS Antibody with Control Lysate

Goat anti-human HRS/HGS antibody recognizes hepatocyte growth factor-regulated tyrosine kinase substrate, also known as protein PP110. This antibody has been extensively validated for western blotting using whole cell lysates.

Product Type
PrecisionAb™ Polyclonal
Isotype
Polyclonal IgG
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
VPA00514 WB 100 µl
VPA00514KT WB 2 Westerns
With Lysate 400µg
Goat anti Human HRS / HGS antibody recognizes HRS / HGS, also known as human growth factor-regulated tyrosine kinase substrate or protein pp110.

The protein encoded by HGS regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these proteins for lysosome-dependent degradation (provided by RefSeq, Dec 2010).

Goat anti Human HRS / HGS antibody detects a band of 110 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Product Form
Purified IgG - liquid
Preparation
Goat polyclonal antibody purified by affinity chromatography
Preparation
20μl Goat polyclonal antibody purified by affinity chromatography
Buffer Solution
TRIS buffered saline
Buffer Solution
TRIS buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
0.5% Bovine Serum Albumin
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
0.5% Bovine Serum Albumin
Immunogen
Peptide sequence C-NRNYWEKKQEEARK

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles
Storage
Antibody: Store undiluted at -20oC, avoiding repeated freeze thaw cycles.

Lysate: Store lyophilized lysate at -20°C. After reconstitution aliquot and store at -20°C for up to 3 months or at -80°C for longer term storage.
Shelf Life
As supplied, 12 months from date of despatch
Shelf Life
As supplied, 12 months from date of despatch

More Information

UniProt
O14964 Related reagents
Entrez Gene
HGS Related reagents
GO Terms
GO:0005829 cytosol
GO:0006886 intracellular protein transport
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0008270 zinc ion binding
GO:0008285 negative regulation of cell proliferation
GO:0016197 endosome transport
GO:0019904 protein domain specific binding
GO:0031901 early endosome membrane
GO:0032585 multivesicular body membrane
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
GO:0042176 regulation of protein catabolic process
GO:0046426 negative regulation of JAK-STAT cascade
Acknowledgements
PrecisionAb™ is a trademark of Bio-Rad Laboratories
Acknowledgements
PrecisionAb™ is a trademark of Bio-Rad Laboratories
Regulatory
For research purposes only

Applications of Hrs / HGS antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
Western Blotting 1/1000

PrecisionAb antibodies have been extensively validated for the western blot application. The antibody has been validated at the suggested dilution. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependant on sample type.

PrecisionAb antibodies have been extensively validated for the western blot application. The antibody has been validated at the suggested dilution. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependant on sample type.
Western Blotting
Anti HRS / HGS detects a band of approximately 110 kDa in HEK293 cell lysates
Western Blotting
Anti HRS / HGS detects a band of approximately 110 kDa in HEK293 cell lysates
Instructions For Use
Please refer to the PrecisionAb western blotting protocol. For additional information on secondary antibody dilution and exposure time see product web page.
Instructions For Use
Please refer to the PrecisionAb western blotting protocol. For additional information on secondary antibody dilution and exposure time see product web page.

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Donkey anti Sheep/Goat IgG:HRP STAR88P 1 ml C E P WB
Donkey anti Sheep/Goat IgG:HRP STAR88P 1 ml C E P WB