Rabbit anti Human hnRNP Q / SYNCRIP antibody recognizes hnRNP Q / SYNCRIP also known as heterogeneous nuclear ribonucleoprotein Q, NS1-associated protein 1, glycine- and tyrosine-rich RNA-binding protein or Synaptotagmin-binding, cytoplasmic RNA-interacting protein.

Encode by the SYNCRIP gene, hnRNP Q is a member of the cellular heterogeneous nuclear ribonucleoprotein (hnRNP) family. hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. The encoded protein plays a role in multiple aspects of mRNA maturation and is associated with several multiprotein complexes including the apoB RNA editing-complex and survival of motor neurons (SMN) complex. Alternatively spliced transcript variants encoding multiple isoforms have been observed for SYNCRIP, and a pseudogene of SYNCRIP is located on the short arm of chromosome 20 (provided by RefSeq, Dec 2011).

Rabbit anti Human hnRNP Q / SYNCRIP antibody detects a band of 65-82 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000