Histone H2BJ antibody
Rabbit anti Human histone H2BJ antibody recognizes Histone H2B type 1J, also known as histone H2B.1 and histone H2B/r.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. The Histone H2BJ gene (HIST1H2BJ) is intron-less and encodes a member of the histone H2B family. Transcripts from HIST1H2BJ lack polyA tails but instead contain a palindromic termination element. HIST1H2BJ is found in the histone microcluster on chromosome 6p21.33 (provided by RefSeq, Jul 2008).
Rabbit anti Human histone H2BJ antibody detects a band of 17 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. The Histone H2BJ gene (HIST1H2BJ) is intron-less and encodes a member of the histone H2B family. Transcripts from HIST1H2BJ lack polyA tails but instead contain a palindromic termination element. HIST1H2BJ is found in the histone microcluster on chromosome 6p21.33 (provided by RefSeq, Jul 2008).
Rabbit anti Human histone H2BJ antibody detects a band of 17 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti histone H2BJ detects a band of approximately 17 kDa in HEK293 cell lysate
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- KLH-conjugated synthetic peptide corresponding to aa 98-126 of human histone H2BJ
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P06899
- Entrez Gene
- HIST1H2BJ
- GO Terms
- GO:0000786 nucleosome
- GO:0003677 DNA binding
- GO:0006334 nucleosome assembly
- GO:0042742 defense response to bacterium
- GO:0005634 nucleus
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
- Regulatory
- For research purposes only
Applications of Histone H2BJ antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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