Histone Deacetylase 6 antibody

Rabbit anti Histone Deacetylase 6

Product Type
PrecisionAb Polyclonal
Polyclonal IgG
Histone Deacetylase 6

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SDS Safety Datasheet SDS
WB 100 µl loader
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Rabbit anti Human histone deacetylase 6 antibody recognizes histone deacetylase 6, also known as HDAC6.

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Encoded by HDAC6 gene, histone deacetylase 6 belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription (provided by RefSeq, Jul 2008).

Rabbit anti Human histone deacetylase 6 antibody detects a band of 160 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Western Blotting
Anti histone deacetylase 6 detects a band of approximately 160 kDa in HEK293 cell lysates.
Product Form
Purified IgG - liquid
Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin
<30% Glycerol
Synthetic peptide corresponding to amino acids close to the N terminus of human histone deacetylase 6
For research purposes only.
12 months from date of despatch.
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description Product Code Applications Pack Size List Price Your Price Quantity
Goat anti Rabbit IgG (H/L):HRP STAR208P WB 2 ml
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Description Goat anti Rabbit IgG (H/L):HRP

Entrez Gene
GO Terms
GO:0000118 histone deacetylase complex
GO:0003779 actin binding
GO:0004407 histone deacetylase activity
GO:0005829 cytosol
GO:0005875 microtubule associated complex
GO:0005901 caveola
GO:0006350 transcription
GO:0006515 misfolded or incompletely synthesized protein catabolic process
GO:0008013 beta-catenin binding
GO:0008017 microtubule binding
GO:0008270 zinc ion binding
GO:0009636 response to toxin
GO:0009967 positive regulation of signal transduction
GO:0010469 regulation of receptor activity
GO:0051879 Hsp90 protein binding
GO:0010634 positive regulation of epithelial cell migration
GO:0010727 negative regulation of hydrogen peroxide metabolic process
GO:0010870 positive regulation of receptor biosynthetic process
GO:0016235 aggresome
GO:0016236 macroautophagy
GO:0016566 specific transcriptional repressor activity
GO:0016575 histone deacetylation
GO:0031252 cell leading edge
GO:0031593 polyubiquitin binding
GO:0032418 lysosome localization
GO:0034983 peptidyl-lysine deacetylation
GO:0042826 histone deacetylase binding
GO:0042903 tubulin deacetylase activity
GO:0043014 alpha-tubulin binding
GO:0043065 positive regulation of apoptosis
GO:0045861 negative regulation of proteolysis
GO:0048156 tau protein binding
GO:0048471 perinuclear region of cytoplasm
GO:0051354 negative regulation of oxidoreductase activity
GO:0060632 regulation of microtubule-based movement
GO:0060765 regulation of androgen receptor signaling pathway
GO:0070301 cellular response to hydrogen peroxide
GO:0070840 dynein complex binding
GO:0070842 aggresome assembly
GO:0070845 polyubiquitinated misfolded protein transport
GO:0070846 Hsp90 deacetylation
GO:0070848 response to growth factor stimulus
GO:0090035 positive regulation of cellular chaperone-mediated protein complex assembly
GO:0090042 tubulin deacetylation



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